Evidence map›Paper›PMID 30984278›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2019

The Antitumor Effect of Curcumin in Urothelial Cancer Cells Is Enhanced by Light Exposure In Vitro.

Frederik Roos, Katherina Binder, Jochen Rutz, Sebastian Maxeiner, August Bernd, Stefan Kippenberger, Nadja Zöller, Felix K-H Chun, Eva Juengel, Roman A Blaheta

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Visible light potentiates rapid cell destruction and death by curcumin in vitro.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Curcumin-A Viable Agent for Better Bladder Cancer Treatment.International journal of molecular sciences · 2020
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Frederik RoosDepartment of Urology, Goethe-University, Frankfurt am Main, Germany.
Katherina BinderDepartment of Urology, Goethe-University, Frankfurt am Main, Germany.
Jochen RutzDepartment of Urology, Goethe-University, Frankfurt am Main, Germany.
Sebastian MaxeinerDepartment of Urology, Goethe-University, Frankfurt am Main, Germany.
August BerndDepartment of Dermatology, Venereology, and Allergology, Goethe-University, Frankfurt am Main, Germany.ORCID 0000-0002-9808-6409
Stefan KippenbergerDepartment of Dermatology, Venereology, and Allergology, Goethe-University, Frankfurt am Main, Germany.ORCID 0000-0001-6157-6773
Nadja ZöllerDepartment of Dermatology, Venereology, and Allergology, Goethe-University, Frankfurt am Main, Germany.
Felix K-H ChunDepartment of Urology, Goethe-University, Frankfurt am Main, Germany.
Eva JuengelDepartment of Urology, Goethe-University, Frankfurt am Main, Germany.
Roman A BlahetaDepartment of Urology, Goethe-University, Frankfurt am Main, Germany.ORCID 0000-0002-0129-7972
Goethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The natural compound curcumin exerts antitumor properties in vitro, but its clinical application is limited due to low bioavailability. Light exposure in skin and skin cancer cells has been shown to improve curcumin bioavailability; thus, the object of this investigation was to determine whether light exposure might also enhance curcumin efficacy in bladder cancer cell lines. RT112, UMUC3, and TCCSUP cells were preincubated with low curcumin concentrations (0.1-0.4

Identifiers

PMID30984278
PMCPMC6432698
OpenAlexW2920897062

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.