Evidence map›Paper›PMID 30984245›Full record

ArticleFrontiers in genetics2019

Assessment of Autozygosity Derived From Runs of Homozygosity in Jinhua Pigs Disclosed by Sequencing Data.

Zhong Xu, Hao Sun, Zhe Zhang, Qingbo Zhao, Babatunde Shittu Olasege, Qiumeng Li, Yang Yue, Peipei Ma, Xiangzhe Zhang, Qishan Wang and 1 more

Abstract read
In one paragraph

Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Natural variation inScience advances · 2026
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  5. Runs of Homozygosity Preliminary Investigation in Pig Breeds.Animals : an open access journal from MDPI · 2025
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  14. The Role ofInternational journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhong XuDepartment of Animal Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Hao SunDepartment of Animal Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Zhe ZhangDepartment of Animal Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Qingbo ZhaoDepartment of Animal Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Babatunde Shittu OlasegeDepartment of Animal Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Qiumeng LiDepartment of Animal Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Yang YueDepartment of Animal Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Peipei MaDepartment of Animal Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Xiangzhe ZhangDepartment of Animal Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Qishan WangDepartment of Animal Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Yuchun PanDepartment of Animal Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.

Funding

Investigation of metabolites related to manganese exposureF31ES027304 · NIEHS · UNIVERSITY OF WASHINGTON · PI BAKER, MARISSA GAYL · 2016 to 2017
$61k
NIEHS NIH HHS 27304C2054
6 · The paper itself

Abstract

Jinhua pig, a well-known Chinese indigenous breed, has evolved as a pig breed with excellent meat quality, greater disease resistance, and higher prolificacy. The reduction in the number of Jinhua pigs over the past years has raised concerns about inbreeding. Runs of homozygosity (ROH) along the genome have been applied to quantify individual autozygosity to improve the understanding of inbreeding depression and identify genes associated with traits of interest. Here, we investigated the occurrence and distribution of ROH using next-generation sequencing data to characterize autozygosity in 202 Jinhua pigs, as well as to identify the genomic regions with high ROH frequencies within individuals. The average inbreeding coefficient, based on ROH longer than 1 Mb, was 0.168 ± 0.052. In total, 18,690 ROH were identified in all individuals, among which shorter segments (1-5 Mb) predominated. Individual ROH autosome coverage ranged from 5.32 to 29.14% in the Jinhua population. On average, approximately 16.8% of the whole genome was covered by ROH segments, with the lowest coverage on SSC11 and the highest coverage on SSC17. A total of 824 SNPs (about 0.5%) and 11 ROH island regions were identified (occurring in over 45% of the samples). Genes associated with reproduction (

Indexed as

animal breedinginbreeding coefficientspigruns of homozygosityselection

Identifiers

PMID30984245
PMCPMC6448551

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