Evidence map›Paper›PMID 30984177›Full record

ArticleFrontiers in immunology2019

Immunogenicity of a Virus-Like-Particle Vaccine Containing Multiple Antigenic Epitopes of

Jingjing Guo, Aihua Zhou, Xiahui Sun, Wenchao Sha, Kang Ai, Ge Pan, Chunxue Zhou, Huaiyu Zhou, Hua Cong, Shenyi He

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. A perspective on SARS-CoV-2 virus-like particles vaccines.International immunopharmacology · 2023
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Advances inVaccines · 2021
    Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jingjing GuoDepartment of Parasitology, School of Basic Medical Sciences, Shandong University, Jinan, China.
Aihua ZhouDepartment of Pediatrics, Provincial Hospital Affiliated to Shandong University, School of Medicine, Shandong University, Jinan, China.
Xiahui SunDepartment of Parasitology, School of Basic Medical Sciences, Shandong University, Jinan, China.
Wenchao ShaDepartment of Parasitology, School of Basic Medical Sciences, Shandong University, Jinan, China.
Kang AiDepartment of Parasitology, School of Basic Medical Sciences, Shandong University, Jinan, China.
Ge PanDepartment of Parasitology, School of Basic Medical Sciences, Shandong University, Jinan, China.
Chunxue ZhouDepartment of Parasitology, School of Basic Medical Sciences, Shandong University, Jinan, China.
Huaiyu ZhouDepartment of Parasitology, School of Basic Medical Sciences, Shandong University, Jinan, China.
Hua CongDepartment of Parasitology, School of Basic Medical Sciences, Shandong University, Jinan, China.
Shenyi HeDepartment of Parasitology, School of Basic Medical Sciences, Shandong University, Jinan, China.
Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is no effective protective vaccine against human toxoplasmosis, which is a potential threat to nearly a third of the world population. Vaccines based on virus-like particles (VLPs) have been highly successful in humans for many years, but have rarely been applied against

Indexed as

Acute DiseaseAnimalsAntigens, ProtozoanChronic DiseaseEpitopes, B-LymphocyteEpitopes, T-LymphocyteFemaleMiceMice, Inbred BALB CProtozoan VaccinesToxoplasmaToxoplasmosisVirionAntigens, ProtozoanEpitopes, B-LymphocyteEpitopes, T-LymphocyteProtozoan VaccinesHBcmultiple antigenic epitopesToxoplasma gondiivaccinevirus-like particles

Identifiers

PMID30984177
PMCPMC6449433
OpenAlexW2927386502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.