Evidence map›Paper›PMID 30984083›Full record

ArticleFrontiers in psychology2019

Cognitive Control as a 5-HT

Scott A Langenecker, Brian J Mickey, Peter Eichhammer, Srijan Sen, Kathleen H Elverman, Susan E Kennedy, Mary M Heitzeg, Saulo M Ribeiro, Tiffany M Love, David T Hsu and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Relations of gray matter volume to dimensional measures of cognition and affect in mood disorders.Cortex; a journal devoted to the study of the nervous system and behavior · 2022
    Article
  4. Correlation betweenTranslational pediatrics · 2022
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Scott A LangeneckerThe Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI, United States.
Brian J MickeyThe Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI, United States.
Peter EichhammerDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, United States.
Srijan SenThe Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI, United States.
Kathleen H ElvermanDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, United States.
Susan E KennedyThe Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI, United States.
Mary M HeitzegThe Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI, United States.
Saulo M RibeiroThe Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI, United States.
Tiffany M LoveThe Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI, United States.
David T HsuThe Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI, United States.
Robert A KoeppeDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, United States.
Stanley J WatsonThe Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI, United States.
Huda AkilThe Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI, United States.
David GoldmanNational Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, United States.
Margit BurmeisterThe Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI, United States.
Jon-Kar ZubietaThe Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI, United States.
University of Michigan–Ann Arbor · USNational Institutes of Health · US

Funding

Integrative genetics of behavior with high throughput technologiesZIAAA000301 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI GOLDMAN, DAVID · 2009 to 2025
$68.6M
Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
MICHIGAN INSTITUTE FOR CLINICAL AND HEALTH RESEARCH (MICHR) (UL1): (BPCA)UL1RR024986 · NCRR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SHANLEY, THOMAS P. · 2007 to 2011
$51.2M
ZINC GLUCONATE GLYCINE LOZENGES &VITAMIN C EFFECTS ON COMMON COLDM01RR000042 · NCRR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ELSTROM, REBECCA L · 1985 to 2007
$40.8M
TISSUE SPECIFIC /INDUCIBLE REGULATION RECEPTORS /TRANSGEP01MH042251 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WATSON, STANLEY J · 1987 to 2006
$8.3M
Dimensional RDoC Modeling across the Range of Negative Mood DysfunctionR01MH101487 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LANGENECKER, SCOTT A · 2013 to 2016
$2.5M
Defining and manipulating social neural systems in alcohol use disorderK01AA024167 · NIAAA · UNIVERSITY OF UTAH · PI LOVE, TIFFANY · 2015 to 2019
$805k
Depression Subtypes: Cognition, Emotion, NeurophysiologyK23MH074459 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LANGENECKER, SCOTT A · 2008 to 2012
$643k
NCATS NIH HHS UL1 TR002240NCRR NIH HHS M01 RR000042NCRR NIH HHS UL1 RR024986NIAAA NIH HHS K01 AA024167NIMH NIH HHS K23 MH074459NIMH NIH HHS P01 MH042251NIMH NIH HHS R01 MH101487
6 · The paper itself

Abstract

Heterogeneity within Major Depressive Disorder (MDD) has hampered identification of biological markers (e.g., intermediate phenotypes, IPs) that might increase risk for the disorder or reflect closer links to the genes underlying the disease process. The newer characterizations of dimensions of MDD within Research Domain Criteria (RDoC) domains may align well with the goal of defining IPs. We compare a sample of 25 individuals with MDD compared to 29 age and education matched controls in multimodal assessment. The multimodal RDoC assessment included the primary IP biomarker, positron emission tomography (PET) with a selective radiotracer for 5-HT

Indexed as

executive functioninginterference resolutionintermediate cognitive phenotypesmajor depressive disorderpositron emission tomographyprocessing speedserotonin

Identifiers

PMID30984083
PMCPMC6450211
OpenAlexW2927069780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.