ArticleFrontiers in psychiatry2019
Emotional Biases and Recurrence in Major Depressive Disorder. Results of 2.5 Years Follow-Up of Drug-Free Cohort Vulnerable for Recurrence.
Article in Frontiers in psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic models for predicting relapse or recurrence of major depressive disorder in adults.The Cochrane database of systematic reviews · 2021Pooled it
- Efficacy of empagliflozin as adjunctive therapy to citalopram in major depressive disorder: a randomized double-blind, placebo-controlled clinical trial.BMC psychiatry · 2024Trial
- Single ayahuasca administration mitigates long-term behavioral and neurochemical effects of early-life stress in rats.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Emotion-Processing Biases and Neural Connectivity in Remitted Major Depressive Disorder among Adolescents.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Reduced alpha power predicts recurrence risk in major depressive disorder.Neuroimage. Reports · 2026Article
- Associations Between Cognitive Functions and Subsequent Mood Disorder Prognosis in Low-Risk, High-Risk and Affected Monozygotic Twins: A Seven-Year Follow-Up Study.Acta psychiatrica Scandinavica · 2026Article
- Transdiagnostic associations between subjective gesture behaviour and objective performance in schizophrenia and depression.Translational psychiatry · 2026Article
- Remission is insufficient: predictors and mechanistic models of recurrence in late-life depression.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- The neurobiological basis of the awe experience in affective disorders: an exploratory EEG study.Frontiers in systems neuroscience · 2026Article
- Smartphone Ecological Momentary Assessment and Wearable Activity Tracking in Pediatric Depression: Cohort Study.JMIR formative research · 2025Article
- Article
- The Chinese version of the immediate mood scaler (IMS): a study evaluating its validity, reliability, and responsiveness in patients with MDD in China.BMC psychiatry · 2025Article
- Personalizing esketamine treatment in TRD and TRBD: the role of mentalization, cognitive rigidity, psychache, and suicidality.Frontiers in psychiatry · 2025Article
- Selective impairment and a positive recognition bias of the facial emotion recognition after propofol anesthesia during gastrointestinal endoscopy.Frontiers in psychology · 2025Article
- Beyond the serotonin deficit hypothesis: communicating a neuroplasticity framework of major depressive disorder.Molecular psychiatry · 2024Review
- Impact of depersonalization on the course of depression: longitudinal observations from the gutenberg health study.BMC psychiatry · 2024Article
- Neural signatures of emotional biases predict clinical outcomes in difficult-to-treat depression.Research directions. Depression · 2024Article
- Emotional Bias among Individuals at Risk for Seasonal Affective Disorder-An EEG Study during Remission in Summer.Brain sciences · 2023Article
- Using digital phenotyping to capture depression symptom variability: detecting naturalistic variability in depression symptoms across one year using passively collected wearable movement and sleep data.Translational psychiatry · 2023Article
- Depression recurrence is accompanied by longer periods in default mode and more frequent attentional and reward processing dynamic brain-states during resting-state activity.Human brain mapping · 2023Article
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Authors and funding
10 authors.
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Abstract
An interesting factor explaining recurrence risk in Major Depressive Disorder (MDD) may be neuropsychological functioning, i.e., processing of emotional stimuli/information. Negatively biased processing of emotional stimuli/information has been found in both acute and (inconclusively) remitted states of MDD, and may be causally related to recurrence of depression. We aimed to investigate self-referent, memory and interpretation biases in recurrently depressed patients in remission and relate these biases to recurrence. We included 69 remitted recurrent MDD-patients (rrMDD-patients), 35-65 years, with ≥2 episodes, voluntarily free of antidepressant maintenance therapy for at least 4 weeks. We tested self-referent biases with an emotional categorization task, bias in emotional memory by free recall of the emotion categorization task 15 min after completing it, and interpretation bias with a facial expression recognition task. We compared these participants with 43 never-depressed controls matched for age, sex and intelligence. We followed the rrMDD-patients for 2.5 years and assessed recurrent depressive episodes by structured interview. The rrMDD-patients showed biases toward emotionally negative stimuli, faster responses to negative self-relevant characteristics in the emotional categorization, better recognition of sad faces, worse recognition of neutral faces with more misclassifications as angry or disgusting faces and less misclassifications as neutral faces (0.001 <
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