Evidence map›Paper›PMID 30984028›Full record

ArticleFrontiers in physiology2019

Incorporation of Omega-3 Fatty Acids Into Human Skeletal Muscle Sarcolemmal and Mitochondrial Membranes Following 12 Weeks of Fish Oil Supplementation.

Christopher J Gerling, Kazutaka Mukai, Adrian Chabowski, George J F Heigenhauser, Graham P Holloway, Lawrence L Spriet, Sebastian Jannas-Vela

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07237113 (Effects of Omega-3 Fatty Acid Supplementation on Muscle Damage and Oxylipin Production Induced by Eccentric Exercise in Young Men), which is not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07237113 nacompletednot on this mapstarted 2021, after this paper: background citation

Effects of Omega-3 Fatty Acid Supplementation on Muscle Damage and Oxylipin Production Induced by Eccentric Exercise in Young Men

TypeinterventionalSponsorInstituto de Ciencias de la Salud, Universidad de O'HigginsRan2021 to 2024Enrolled30ConditionsDamage MuscleArmsPlacebo, Omega
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 52 citations in OpenAlex.

  1. Trial
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  7. The Role of Omega-3 Polyunsaturated Fatty Acids on Sarcopenia and Aging Muscle.International journal of environmental research and public health · 2026
    Review
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  10. Article
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  20. Assessment of Polyunsaturated Fatty Acids on COVID-19-Associated Risk Reduction.Revista brasileira de farmacognosia : orgao oficial da Sociedade Brasileira de Farmacognosia · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Christopher J GerlingDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, Canada.
Kazutaka MukaiDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, Canada.
Adrian ChabowskiDepartment of Physiology, Medical University of Białystok, Białystok, Poland.
George J F HeigenhauserDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Graham P HollowayDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, Canada.
Lawrence L SprietDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, Canada.
Sebastian Jannas-VelaDepartment of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, Canada.
University of Guelph · CAMcMaster University · CAMedical University of Białystok · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fish oil (FO) supplementation in humans results in the incorporation of omega-3 fatty acids (FAs) eicosapentaenoic acid (EPA; C20:5) and docosahexaenoic acid (DHA; C20:6) into skeletal muscle membranes. However, despite the importance of membrane composition in structure-function relationships, a paucity of information exists regarding how different muscle membranes/organelles respond to FO supplementation. Therefore, the purpose of the present study was to determine the effects 12 weeks of FO supplementation (3g EPA/2g DHA daily) on the phospholipid composition of sarcolemmal and mitochondrial fractions, as well as whole muscle responses, in healthy young males. FO supplementation increased the total phospholipid content in whole muscle (57%;

Indexed as

fatty acidsmembranemitochondriaomega-3sarcolemmaskeletal muscle

Identifiers

PMID30984028
PMCPMC6449797
OpenAlexW2932545931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.