Evidence map›Paper›PMID 30983912›Full record

ArticleClinical reviews in bone and mineral metabolism2018

Clinical measurements of bone tissue mechanical behavior using reference point indentation.

Andrew Chang, Garrett W Easson, Simon Y Tang

Abstract read
In one paragraph

Article in Clinical reviews in bone and mineral metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. 3D Imaging of Indentation Damage in Bone.Materials (Basel, Switzerland) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andrew ChangDepartment of Mechanical Engineering and Materials Science, Washington University in St. Louis, St. Louis, MO.
Garrett W EassonDepartment of Mechanical Engineering and Materials Science, Washington University in St. Louis, St. Louis, MO.
Simon Y TangDepartment of Mechanical Engineering and Materials Science, Washington University in St. Louis, St. Louis, MO.

Funding

The Role of the Osteoblast Secretome in Bone FormationP30AR057235 · NIAMS · WASHINGTON UNIVERSITY · PI VEIS, DEBORAH J · 2009 to 2018
$5.7M
Tissue Level Deformations of the Loaded Spine in Humans with Low Back PainK01AR069116 · NIAMS · WASHINGTON UNIVERSITY · PI TANG, SIMON YUE-CHEONG · 2016 to 2019
$489k
Effects of Ages and Rage on IVD Degeneration And InflammationR21AR069804 · NIAMS · WASHINGTON UNIVERSITY · PI TANG, SIMON YUE-CHEONG · 2017 to 2018
$369k
NIAMS NIH HHS K01 AR069116NIAMS NIH HHS P30 AR057235NIAMS NIH HHS R21 AR069804
6 · The paper itself

Abstract

Over the last thirty years, it has become increasingly clear the amount of bone (e.g. 'bone quantity') and the quality of the bone matrix (e.g. 'bone quality') both critically contribute to bone's tissue-level mechanical behavior and the subsequent ability of bone to resist fracture. Although determining the tissue-level mechanical behavior of bone through mechanical testing is relatively straightforward in the laboratory, the destructive nature of such testing is unfeasible in humans and in animal models requiring longitudinal observation. Therefore, surrogate measurements are necessary for quantifying tissue-level mechanical behavior for the pre-clinical and clinical evaluation of bone strength and fracture risk

Indexed as

Biodentbone qualityBone strengthfracture riskOsteoprobereference point indentation

Identifiers

PMID30983912
PMCPMC6457660

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.