Evidence map›Paper›PMID 30983879›Full record

ArticleMediators of inflammation2019

Exploring the Involvement of NLRP3 and IL-1

Antonella Fioravanti, Sara Tenti, Megan McAllister, Melody Chemaly, Amanda Eakin, Joseph McLaughlin, Anthony J Bjourson, Elena Frati, Victoria McGilligan, Sara Cheleschi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Antonella FioravantiRheumatology Unit, Department of Surgery, Medicine and Neurosciences, Le Scotte Hospital, Siena, Italy.ORCID 0000-0002-7325-5579
Sara TentiRheumatology Unit, Department of Surgery, Medicine and Neurosciences, Le Scotte Hospital, Siena, Italy.ORCID 0000-0002-6011-7134
Megan McAllisterNorthern Ireland Centre for Stratified Medicine, University of Ulster, Biomedical Sciences, Research Institute, Londonderry, UK.
Melody ChemalyNorthern Ireland Centre for Stratified Medicine, University of Ulster, Biomedical Sciences, Research Institute, Londonderry, UK.
Amanda EakinNorthern Ireland Centre for Stratified Medicine, University of Ulster, Biomedical Sciences, Research Institute, Londonderry, UK.
Joseph McLaughlinNorthern Ireland Centre for Stratified Medicine, University of Ulster, Biomedical Sciences, Research Institute, Londonderry, UK.
Anthony J BjoursonNorthern Ireland Centre for Stratified Medicine, University of Ulster, Biomedical Sciences, Research Institute, Londonderry, UK.
Elena FratiRheumatology Unit, Department of Surgery, Medicine and Neurosciences, Le Scotte Hospital, Siena, Italy.
Victoria McGilliganNorthern Ireland Centre for Stratified Medicine, University of Ulster, Biomedical Sciences, Research Institute, Londonderry, UK.ORCID 0000-0003-1013-3504
Sara CheleschiRheumatology Unit, Department of Surgery, Medicine and Neurosciences, Le Scotte Hospital, Siena, Italy.
David S GibsonNorthern Ireland Centre for Stratified Medicine, University of Ulster, Biomedical Sciences, Research Institute, Londonderry, UK.
University of Ulster · GBOspedale Santa Maria alle Scotte · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hand osteoarthritis (HOA) includes different subsets; a particular and uncommon form is erosive HOA (EHOA). Interleukin- (IL-) 1

Indexed as

AgedBlotting, WesternCaspase 1Cells, CulturedFemaleHand JointsHumansInflammasomesInterleukin-17Interleukin-1betaInterleukin-6MaleMiddle AgedNLR Family, Pyrin Domain-Containing 3 ProteinOsteoarthritisPilot ProjectsCaspase 1InflammasomesInterleukin-17Interleukin-1betaInterleukin-6NLR Family, Pyrin Domain-Containing 3 ProteinTumor Necrosis Factor-alpha

Identifiers

PMID30983879
PMCPMC6431515
OpenAlexW2921039027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.