Evidence map›Paper›PMID 30983696›Full record

ArticleJournal of physical organic chemistry2018

Improving the Fluorescent Probe Acridonylalanine Through a Combination of Theory and Experiment.

Itthipol Sungwienwong, John J Ferrie, Joomyung V Jun, Chunxiao Liu, Taylor M Barrett, Zachary M Hostetler, Naoya Ieda, Amara Hendricks, Anand K Muthusamy, Rahul M Kohli and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of physical organic chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Synthesis and characterization of fluorescent amino acid dimethylaminoacridonylalanine.ARKIVOC : free online journal of organic chemistry · 2021
    Article
  8. Light-Emitting Probes for Labeling Peptides.Cell reports. Physical science · 2020
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Itthipol Sungwienwong *Department of Chemistry, University of Pennsylvania, 213 South 34th Street, Philadelphia, PA 19104, USA.
John J Ferrie *Department of Chemistry, University of Pennsylvania, 213 South 34th Street, Philadelphia, PA 19104, USA.
Joomyung V JunDepartment of Chemistry, University of Pennsylvania, 213 South 34th Street, Philadelphia, PA 19104, USA.
Chunxiao LiuDepartment of Chemistry, University of Pennsylvania, 213 South 34th Street, Philadelphia, PA 19104, USA.
Taylor M BarrettDepartment of Chemistry, University of Pennsylvania, 213 South 34th Street, Philadelphia, PA 19104, USA.
Zachary M HostetlerDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, 3610 Hamilton Walk, Philadelphia, PA 19104, USA.
Naoya IedaDepartment of Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1, Tanabedori, Mizuho-ku, Nagoya-shi, Aichi 467-8603, Japan.
Amara HendricksDepartment of Chemistry, University of Pennsylvania, 213 South 34th Street, Philadelphia, PA 19104, USA.
Anand K MuthusamyDepartment of Chemistry, University of Pennsylvania, 213 South 34th Street, Philadelphia, PA 19104, USA.
Rahul M KohliDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, 3610 Hamilton Walk, Philadelphia, PA 19104, USA.
David M ChenowethDepartment of Chemistry, University of Pennsylvania, 213 South 34th Street, Philadelphia, PA 19104, USA.
George A PeterssonTemple University Institute for Computational Molecular Science, 1925 N. 12th St., Philadelphia, PA 19122, USA.
E James PeterssonDepartment of Chemistry, University of Pennsylvania, 213 South 34th Street, Philadelphia, PA 19104, USA.

Funding

Predoctoral Training at the Chemistry-Biology InterfaceT32GM071339 · NIGMS · WISTAR INSTITUTE · PI MARMORSTEIN, RONEN, SPEICHER, DAVID W. · 2005 to 2019
$3.2M
Predoctoral Training at the Chemistry-Biology InterfaceT32GM133398 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Ronen Marmorstein, Ernest James Petersson · 2020 to 2026
$2.4M
Protocol Driven Hemodynamic Support in Septic ShockK23GM071399 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI SEVRANSKY, JONATHAN E · 2005 to 2009
$671k
NMR SYSTEMS : 2 BRUKER AVANCE 500 CONSOLESS10RR022442 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI SMITH, AMOS B · 2006 to 2006
$500k
Time-Of-Flight Instrument with Variable Ionization SourcesS10RR023444 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI DMOCHOWSKI, IVAN JULIAN · 2007 to 2007
$308k
NCRR NIH HHS S10 RR022442NCRR NIH HHS S10 RR023444NIGMS NIH HHS K23 GM071399NIGMS NIH HHS T32 GM071339NIGMS NIH HHS T32 GM133398
6 · The paper itself

Abstract

Acridonylalanine (Acd) is a useful fluorophore for studying proteins by fluorescence spectroscopy, but it can potentially be improved by being made longer wavelength or brighter. Here, we report the synthesis of Acd core derivatives and their photophysical characterization. We also performed

Indexed as

Acridoneamino acidelectronic structure calculationfluorescence spectroscopy

Identifiers

PMID30983696
PMCPMC6454874

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.