Evidence map›Paper›PMID 30983590›Full record

ReviewLancet (London, England)2019

Inappropriate opioid prescription after surgery.

Mark D Neuman, Brian T Bateman, Hannah Wunsch

4 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Lancet (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 162 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
162citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04813991 phase3withdrawnnot on this mapstarted 2022, after this paper: background citation

Achieving Peri-Operative Pain Control Without Opioids

TypeinterventionalSponsorHackensack Meridian HealthRan2022 to 2025Enrolled0ConditionsPerioperative PainArmsIbuprofen 600 mg, OxyCODONE 5 Mg Oral Capsule
NCT05575999 phase1not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Pain Management in Cardiac Implantable Electronic Device Insertion; Effectiveness of Bupivacaine, Ketorolac, Ketamine, vs Bupivacaine Alone in Reducing Postoperative Pocket Pain

TypeinterventionalSponsorKansas City Heart Rhythm Research FoundationRan2026 to 2026Enrolled200ConditionsPain ManagementArmsBupivacaine alone OR Bupivacaine-Ketorolac-Ketamine (BKK) Combination
NCT06270654 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Management of Perioperative Pain Using Erector Spinae Plane Block in Open Microscopic Lumbar Surgery

TypeinterventionalSponsorUniversity of MalayaRan2023 to 2024Enrolled40ConditionsLumbar Spine DiseaseArmsErector spinae plane block, Skin infiltration LA
NCT07510373 narecruitingnot on this mapstarted 2026, after this paper: background citation

Opioid Tapering After Hospital Discharge: Testing an Intervention to Improve Post-operative

TypeinterventionalSponsorMontefiore Medical CenterRan2026 to 2028Enrolled42ConditionsOpioid TaperingArmsTreatment as Usual (TAU), Telephonic Support (TS) Providers, DOTS Intervention
3 · Its place in the literature

Who cites it

162 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
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  3. CDC Clinical Practice Guideline for Prescribing Opioids for Pain - United States, 2022.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2022
    Guideline
  4. Pooled it
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  6. Pooled it
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  8. Trial
  9. Opioid Analgesia Following Pediatric Adenotonsillectomy: A Randomized Clinical Trial.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Trial
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  18. Observational
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102 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Mark D NeumanDepartment of Anesthesiology and Critical Care, Perelman School of Medicine and Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA.
Brian T BatemanDepartment of Anesthesia, Perioperative, and Pain Medicine, and Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: bbateman@bwh.harvard.edu.
Hannah WunschDepartment of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; Sunnybrook Research Institute, Toronto, ON, Canada; Department of Anesthesia and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.

Funding

The Impact of Prescription Opioid Use on Pregnancy OutcomesR01DA044293 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI BATEMAN, BRIAN THOMAS · 2017 to 2020
$2.1M
Acute Pain Management and Long-term Opioid Use after SurgeryR01DA042299 · NIDA · SUNNYBROOK RESEARCH INSTITUTE · PI NEUMAN, MARK DAVID, WUNSCH, HANNAH · 2017 to 2020
$2.0M
NIDA NIH HHS R01 DA042299NIDA NIH HHS R01 DA044293
6 · The paper itself

Abstract

Worldwide, the use of prescription opioid analgesics more than doubled between 2001 and 2013, with several countries, including the USA, Canada, and Australia, experiencing epidemics of opioid misuse and abuse over this period. In this context, excessive prescribing of opioids for pain treatment after surgery has been recognised as an important concern for public health and a potential contributor to patterns of opioid misuse and related harm. In the second paper in this Series we review the evolution of prescription opioid use for pain treatment after surgery in the USA, Canada, and other countries. We summarise evidence on the extent of opioid overprescribing after surgery and its potential association with subsequent opioid misuse, diversion, and the development of opioid use disorder. We discuss evidence on patient, physician, and system-level predictors of excessive prescribing after surgery, and summarise recent work on clinical and policy efforts to reduce such prescribing while ensuring adequate pain control.

Indexed as

Inappropriate PrescribingAnalgesics, OpioidHumansPostoperative PainAnalgesics, Opioid

Identifiers

PMID30983590
PMCPMC6556783

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.