Evidence map›Paper›PMID 30983504›Full record

ArticleEpigenetics2019

The rs17084733 variant in the

Gloria Ravegnini, César Serrano, Vittorio Simeon, Giulia Sammarini, Margherita Nannini, Erica Roversi, Milena Urbini, Fabrizio Ferrè, Riccardo Ricci, Giuseppe Tarantino and 3 more

Open access · greenAbstract read
In one paragraph

Article in Epigenetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Gloria Ravegninia Department of Pharmacy and Biotechnology , University of Bologna , Bologna , Italy.ORCID 0000-0002-7774-402X
César Serranob Medical Oncology Department , Vall d'Hebron Institute of Oncology, Vall d'Hebron University Hospital , Barcelona , Spain.
Vittorio Simeonc Medical Statistics Unit , University of Campania "Luigi Vanvitelli" , Naples , Italy.
Giulia Sammarinia Department of Pharmacy and Biotechnology , University of Bologna , Bologna , Italy.
Margherita Nanninid Department of Specialized, Experimental and Diagnostic Medicine, Sant'Orsola-Malpighi Hospital , University of Bologna , Bologna , Italy.
Erica Roversia Department of Pharmacy and Biotechnology , University of Bologna , Bologna , Italy.
Milena Urbinie "Giorgio Prodi" Cancer Research Center , University of Bologna , Bologna , Italy.
Fabrizio Ferrèa Department of Pharmacy and Biotechnology , University of Bologna , Bologna , Italy.ORCID 0000-0003-2768-5305
Riccardo Riccif UOC di Anatomia Patologica, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy.ORCID 0000-0002-9089-5084
Giuseppe Tarantinoe "Giorgio Prodi" Cancer Research Center , University of Bologna , Bologna , Italy.ORCID 0000-0002-6078-6856
Maria A Pantaleod Department of Specialized, Experimental and Diagnostic Medicine, Sant'Orsola-Malpighi Hospital , University of Bologna , Bologna , Italy.
Patrizia Hreliaa Department of Pharmacy and Biotechnology , University of Bologna , Bologna , Italy.ORCID 0000-0002-8415-3711
Sabrina Angelinia Department of Pharmacy and Biotechnology , University of Bologna , Bologna , Italy.ORCID 0000-0002-1609-0421
University of Bologna · ITIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Campania "Luigi Vanvitelli" · ITVall d'Hebron Hospital Universitari · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several miRNAs are dysregulated in gastrointestinal stromal tumours (GIST), and miR-221/222 appear to have a prominent role in GIST biology. Therefore, we investigated the role of DNA variants located in miR-221/222 precursor sequences and their target

Indexed as

Polymorphism, Single Nucleotide3' Untranslated RegionsAdultAgedAged, 80 and overApoptosisBinding SitesBiomarkers, TumorCase-Control StudiesCell ProliferationDisease SusceptibilityFemaleFollow-Up StudiesGastrointestinal NeoplasmsGastrointestinal Stromal TumorsGene Expression Regulation, Neoplastic3' Untranslated RegionsBiomarkers, TumorKIT protein, humanMicroRNAsMIR221, humanMIR222, humanProto-Oncogene Proteins c-kitepigeneticsgastrointestinal stromal tumorGISTimatinibKITmiR-221/222miRNA spongemiRSNPSNP

Identifiers

PMID30983504
PMCPMC6557610
OpenAlexW2938096234

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.