Evidence map›Paper›PMID 30983204›Full record

ReviewZhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery2019

[Progress of research on the relationship between calcitonin gene-related peptide and RANK/RANKL/OPG system in the bone reconstruction].

Shiyao Wang, Shaoce Xu, Zhengwei Shi, Jianchao Wu, Shuanhu Lei, Yuliang Wang

Open access · greenAbstract readReview
In one paragraph

Review in Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shiyao WangDepartment of Orthopedics, Lanzhou University Second Hospital, Lanzhou Gansu, 730000, P.R.China;Orthopedics Key Laboratory of Gansu Province, Lanzhou Gansu, 730000, P.R.China.
Shaoce XuDepartment of Orthopedics, Lanzhou University Second Hospital, Lanzhou Gansu, 730000, P.R.China;Orthopedics Key Laboratory of Gansu Province, Lanzhou Gansu, 730000, P.R.China.
Zhengwei ShiDepartment of Orthopedics, Lanzhou University Second Hospital, Lanzhou Gansu, 730000, P.R.China;Orthopedics Key Laboratory of Gansu Province, Lanzhou Gansu, 730000, P.R.China.
Jianchao WuDepartment of Orthopedics, Lanzhou University Second Hospital, Lanzhou Gansu, 730000, P.R.China;Orthopedics Key Laboratory of Gansu Province, Lanzhou Gansu, 730000, P.R.China.
Shuanhu LeiDepartment of Orthopedics, Lanzhou University Second Hospital, Lanzhou Gansu, 730000, P.R.China.
Yuliang WangDepartment of Orthopedics, Lanzhou University Second Hospital, Lanzhou Gansu, 730000, P.R.China.wyl60918@sina.com.
Lanzhou University Second Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo summarize the research progress on the calcitonin gene-related peptide (CGRP) and receptor activator of nuclear factor κB (RANK)/receptor activator of nuclear factor κB ligand (RANKL)/osteoprotegerin (OPG) system during bone reconstruction to provide theoretical basis for further research on the prevention and treatment of bone-related diseases.

methodsThe relevant research results at home and abroad in recent years were analyzed and summarized.

resultsCGRP and RANK/RANKL/OPG system play important regulatory roles in the bone reconstruction.

conclusionAt present, the research on the mechanism of CGRP and RANK/RANKL/OPG system in bone reconstruction is insufficient. Therefore, it is necessary to study further on the process and interrelation of CGRP and RANK/RANKL/OPG system in bone reconstruction to confirm their mechanism, which will bring new ideas and methods for the treatment of bone related diseases in clinic.

Indexed as

Calcitonin Gene-Related PeptideOsteoprotegerinRANK LigandReceptor Activator of Nuclear Factor-kappa BBone RemodelingCalcitoninCarrier ProteinsGlycoproteinsMembrane GlycoproteinsNF-kappa BReceptors, Cytoplasmic and NuclearCalcitoninCalcitonin Gene-Related PeptideCarrier ProteinsGlycoproteinsMembrane GlycoproteinsNF-kappa BOsteoprotegerinRANK LigandReceptor Activator of Nuclear Factor-kappa BReceptors, Cytoplasmic and NuclearBone reconstructioncalcitonin gene-related peptideosteoblastosteoclastosteoprotegerinreceptor activator of nuclear factor κBreceptor activator of nuclear factor κB ligand

Identifiers

PMID30983204
PMCPMC8337187
OpenAlexW2997623433

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.