Evidence map›Paper›PMID 30982877›Full record

SynthesisThe American journal of clinical nutrition2019

Infant milk-feeding practices and diabetes outcomes in offspring: a systematic review.

Darcy Güngör, Perrine Nadaud, Concetta C LaPergola, Carol Dreibelbis, Yat Ping Wong, Nancy Terry, Steve A Abrams, Leila Beker, Tova Jacobovits, Kirsi M Järvinen and 6 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The American journal of clinical nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. The importance of nutrition in pregnancy and lactation: lifelong consequences.American journal of obstetrics and gynecology · 2022
    Review
  14. Article
  15. Endocrine Disrupting Chemicals and Type 1 Diabetes.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Darcy GüngörPanum Group, Bethesda, MD.
Perrine NadaudPanum Group, Bethesda, MD.
Concetta C LaPergolaPanum Group, Bethesda, MD.
Carol DreibelbisPanum Group, Bethesda, MD.
Yat Ping WongUSDA, Food and Nutrition Service, Alexandria, VA.
Nancy TerryNational Institutes of Health Library, Bethesda, MD.
Steve A AbramsDell Medical School at the University of Texas, Austin, TX.
Leila BekerUS Food and Drug Administration, contractor, College Park, MD.
Tova JacobovitsUS Food and Drug Administration, College Park, MD.
Kirsi M JärvinenUniversity of Rochester Medical Center, Rochester, NY.
Laurie A Nommsen-RiversUniversity of Cincinnati College of Allied Health Sciences, Cincinnati, OH.
Kimberly O O'BrienDivision of Nutritional Sciences, Cornell University, Ithaca, NY.
Emily OkenDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA and Department of Nutrition, Harvard School of Public Health, Boston, MA.
Rafael Pérez-EscamillaDepartment of Social and Behavioral Sciences, Yale School of Public Health, New Haven, CT.
Ekhard E ZieglerDepartment of Pediatrics, The University of Iowa, Iowa City, IA.
Joanne M SpahnUSDA, Food and Nutrition Service, Alexandria, VA.

Funding

VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI Martha Susiarjo · 1985 to 2026
$42.8M
Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
NIDDK NIH HHS P30 DK092924NIEHS NIH HHS P30 ES001247
6 · The paper itself

Abstract

backgroundDuring the Pregnancy and Birth to 24 Months Project, the US Departments of Agriculture and Health and Human Services initiated a review of evidence on diet and health in these populations.

objectivesThe aim of these systematic reviews was to examine the relation of 1) never versus ever feeding human milk, 2) shorter versus longer durations of any human milk feeding, 3) shorter versus longer durations of exclusive human milk feeding, and 4) feeding a lower versus higher intensity of human milk to mixed-fed infants with type 1 and type 2 diabetes in offspring.

methodsThe Nutrition Evidence Systematic Review team conducted systematic reviews with external experts. We searched CINAHL, Cochrane, Embase, and PubMed for articles published January 1980-March 2016, dual-screened the results according to predetermined criteria, extracted data from and assessed the risk of bias for each included study, qualitatively synthesized the evidence, developed conclusion statements, and graded the strength of the evidence.

resultsThe 4 systematic reviews included 21, 37, 18, and 1 articles, respectively. Observational evidence suggests that never versus ever feeding human milk (limited evidence) and shorter versus longer durations of any (moderate evidence) and exclusive (limited evidence) human milk feeding are associated with higher type 1 diabetes risk. Insufficient evidence examined type 2 diabetes. Limited evidence suggests that the durations of any and exclusive human milk feeding are not associated with intermediate outcomes (e.g., fasting glucose, insulin resistance) during childhood.

conclusionsLimited to moderate evidence suggests that feeding less or no human milk is associated with higher risk of type 1 diabetes in offspring. Limited evidence suggests no associations between the durations of any and exclusive human milk feeding and intermediate diabetes outcomes in children. Additional research is needed on infant milk-feeding practices and type 2 diabetes and intermediate outcomes in US populations, which may have distinct metabolic risk.

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2DietFeeding BehaviorInfant FormulaMilk, HumanBreast FeedingChildHumansInfantInfant, NewbornInfant Nutritional Physiological Phenomenabreastfeedingbreast milkdiabetesfasting glucosehuman milkinsulin resistancesystematic review

Identifiers

PMID30982877
PMCPMC6500931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.