Evidence map›Paper›PMID 30982806›Full record

ArticleThe Journal of veterinary medical science2019

Estimation of prion infectivity in tissues of cattle infected with atypical BSE by real time-quaking induced conversion assay.

Kazuhei Sawada, Akio Suzuki, Takeshi Yamasaki, Yoshifumi Iwamaru, Yuichi Matsuura, Kohtaro Miyazawa, Kentaro Masujin, Ryuichiro Atarashi, Motohiro Horiuchi

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of veterinary medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The Journal of general virology · 2020
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kazuhei SawadaLaboratory of Veterinary Hygiene, Faculty of Veterinary Medicine, Hokkaido University, Kita18, Nish 9, Kita-ku, Sapporo, Hokkaido 060-0818, Japan.
Akio SuzukiLaboratory of Veterinary Hygiene, Faculty of Veterinary Medicine, Hokkaido University, Kita18, Nish 9, Kita-ku, Sapporo, Hokkaido 060-0818, Japan.
Takeshi YamasakiLaboratory of Veterinary Hygiene, Faculty of Veterinary Medicine, Hokkaido University, Kita18, Nish 9, Kita-ku, Sapporo, Hokkaido 060-0818, Japan.
Yoshifumi IwamaruGlobal Station for Zoonosis Control, Global Institute for Collaborative Research and Education, Hokkaido University, Kita 20, Nishi 10, Kita-ku, Hokkaido 001-0020, Japan.
Yuichi MatsuuraPrion Disease Research Center, National Institute of Animal Health, 3-1-5, Kannondai, Tsukuba, Ibaraki 305-0856, Japan.
Kohtaro MiyazawaPrion Disease Research Center, National Institute of Animal Health, 3-1-5, Kannondai, Tsukuba, Ibaraki 305-0856, Japan.
Kentaro MasujinPrion Disease Research Center, National Institute of Animal Health, 3-1-5, Kannondai, Tsukuba, Ibaraki 305-0856, Japan.
Ryuichiro AtarashiDivision of Microbiology, Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, 5200, Kihara, Kiyotake-cho, Miyazaki, Miyazaki 889-1692, Japan.
Motohiro HoriuchiLaboratory of Veterinary Hygiene, Faculty of Veterinary Medicine, Hokkaido University, Kita18, Nish 9, Kita-ku, Sapporo, Hokkaido 060-0818, Japan.
Hokkaido University · JPNational Institute of Animal Health · JPUniversity of Miyazaki · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atypical bovine spongiform encephalopathy (BSE), first identified in 2004, poses a threat due to the potential to spread the disease to cattle and other animals, including humans. Here, we estimated prion titers in various tissues of cattle infected with atypical BSE using a real-time quaking-induced conversion assay that detects amyloid seeding activity of a disease-specific prion protein, PrP

Indexed as

Encephalopathy, Bovine SpongiformAnimalsCattleImmunoblottingPeripheral NervesPrion ProteinsPrionsTissue DistributionPrion ProteinsPrionsatypical bovine spongiform encephalopathyH-BSEL-BSEprionRT-QuIC

Identifiers

PMID30982806
PMCPMC6612489
OpenAlexW2939479369

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.