ArticleCell2019
Primate Amygdala Neurons Simulate Decision Processes of Social Partners.
Article in Cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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Who cites it
63 citing papers in PubMed.
- An amygdala-mediated simulation-to-decision cascade aligns interbrain dynamics to solve social dilemmas.Nature neuroscience · 2026Article
- Computational origins of cortical brain circuits for social cognition.Nature reviews. Neuroscience · 2026Review
- The social dimension of apathy: evidence for a distinct domain from 11,243 individuals across health and neurocognitive disorders.Translational psychiatry · 2026Article
- Selective observation following betrayal shapes the social inference landscape.PLoS computational biology · 2026Article
- Primate neuroethology: a new synthesis.Trends in cognitive sciences · 2026Review
- Cooperation: Behavioral manifestations and neural mechanisms.Current opinion in neurobiology · 2026Review
- Value coding by primate amygdala neurons complies with the continuity axiom of economic choice theory.Journal of neurophysiology · 2026Article
- Article
- Brain mechanisms underlying self-other distinction for bodily self-recognition.Frontiers in neural circuits · 2026Review
- Clarifying the neural circuit mechanisms of spontaneous social behavior in macaques.Frontiers in neural circuits · 2026Article
- Preferences for fat, sugar, and oral-sensory food qualities in monkeys and humans.Physiology & behavior · 2025Review
- Reward monitoring in the frontopolar cortex of macaques.Scientific reports · 2025Article
- Home-Cage Training for Non-Human Primates: An Opportunity to Reduce Stress and Study Natural Behavior in Neurophysiology Experiments.Animals : an open access journal from MDPI · 2025Review
- Dynamic coding and sequential integration of multiple reward attributes by primate amygdala neurons.Nature communications · 2025Article
- Social Risk Coding by Amygdala Activity and Connectivity with the Dorsal Anterior Cingulate Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Microglia Morphology in the Developing Primate Amygdala and Effects of Early Life Stress.eNeuro · 2025Article
- Representation of Anticipated Rewards and Punishments in the Human Brain.Annual review of psychology · 2025Review
- The human social cognitive network contains multiple regions within the amygdala.Science advances · 2024Article
- A computational signature of self-other mergence in Borderline Personality Disorder.Translational psychiatry · 2024Article
- Decision-Making with Predictions of Others' Likely and Unlikely Choices in the Human Brain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
3 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
Abstract
By observing their social partners, primates learn about reward values of objects. Here, we show that monkeys' amygdala neurons derive object values from observation and use these values to simulate a partner monkey's decision process. While monkeys alternated making reward-based choices, amygdala neurons encoded object-specific values learned from observation. Dynamic activities converted these values to representations of the recorded monkey's own choices. Surprisingly, the same activity patterns unfolded spontaneously before partner's choices in separate neurons, as if these neurons simulated the partner's decision-making. These "simulation neurons" encoded signatures of mutual-inhibitory decision computation, including value comparisons and value-to-choice conversions, resulting in accurate predictions of partner's choices. Population decoding identified differential contributions of amygdala subnuclei. Biophysical modeling of amygdala circuits showed that simulation neurons emerge naturally from convergence between object-value neurons and self-other neurons. By simulating decision computations during observation, these neurons could allow primates to reconstruct their social partners' mental states.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.