Mayo Anesthesia Safety in Kids continued: two new studies and a potential redirection of the field.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

16 citing papers in PubMed.

1. Effects of Sevoflurane on the Development of a Human Brain Microphysiological System.International journal of molecular sciences · 2026
   Article
2. [Interpretation of Standard on Clinical Dental Treatment for Children under General Anesthesia Orsedation].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2025
   Article
3. Human neuron chimeric mice reveal impairment of DVL-1-mediated neuronal migration by sevoflurane and potential treatment by rTMS.Experimental & molecular medicine · 2025
   Article
4. Anesthetic neurotoxicity in the developing brain: an update on theinsights and implications for fetal surgery.Anesthesia and pain medicine · 2024
   Article
5. Risk of Pediatric Bipolar Disorder After General Anesthesia in Infants and Toddlers: A Propensity Score-Matched Population-Based Cohort Study.Schizophrenia bulletin · 2024
   Article
6. Early Postnatal Exposure to Midazolam Causes Lasting Histological and Neurobehavioral Deficits via Activation of the mTOR Pathway.International journal of molecular sciences · 2024
   Article
7. Neurobehavioral effects of general anesthesia and cochlear implantation on hearing-impaired infants: A prospective observational cohort study.Brain and behavior · 2023
   Observational
8. The Effects of Propofol on a HumanFrontiers in cellular neuroscience · 2022
   Article
9. Identification of Prefrontal Cortex and Amygdala Expressed Genes Associated With Sevoflurane Anesthesia on Non-human Primate.Frontiers in integrative neuroscience · 2022
   Article
10. Astrogliosis in juvenile non-human primates 2 years after infant anaesthesia exposure.British journal of anaesthesia · 2021
    Article
11. Early Isoflurane Exposure Impairs Synaptic Development in Fmr1 KO Mice via the mTOR Pathway.Neurochemical research · 2021
    Article
12. General anesthesia affecting on developing brain: evidence from animal to clinical research.Journal of anesthesia · 2020
    Review
13. Exposure to Surgery and Anesthesia in Early Childhood and Subsequent Use of Attention Deficit Hyperactivity Disorder Medications.Anesthesia and analgesia · 2020
    Observational
14. Neonatal sevoflurane exposure induces impulsive behavioral deficit through disrupting excitatory neurons in the medial prefrontal cortex in mice.Translational psychiatry · 2020
    Article
15. Dusp4 Contributes to Anesthesia Neurotoxicity via Mediated Neural Differentiation in Primates.Frontiers in cell and developmental biology · 2020
    Article
16. Effects of Early Exposure of Isoflurane on Chronic Pain via the Mammalian Target of Rapamycin Signal Pathway.International journal of molecular sciences · 2019
    Article

Corrections and comments

• Comment on
  Patterns of neuropsychological changes after general anaesthesia in young children: secondary analysis of the Mayo Anesthesia Safety in Kids study.2019

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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