Evidence map›Paper›PMID 30982491›Full record

ArticleOncology research2019

RAS-Responsive Element-Binding Protein 1 Blocks the Granulocytic Differentiation of Myeloid Leukemia Cells.

Juanjuan Yao, Liang Zhong, Pengqiang Zhong, Dongdong Liu, Zhen Yuan, Junmei Liu, Shifei Yao, Yi Zhao, Min Chen, Lianwen Li and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Retinoic acid and microRNA.Methods in enzymology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Juanjuan YaoCentral Laboratory of Yong Chuan Hospital, Chongqing Medical University, Chongqing, P.R. China.
Liang ZhongKey Laboratory of Laboratory Medical Diagnostics, Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing, P.R. China.
Pengqiang ZhongCentral Laboratory of Yong Chuan Hospital, Chongqing Medical University, Chongqing, P.R. China.
Dongdong LiuKey Laboratory of Laboratory Medical Diagnostics, Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing, P.R. China.
Zhen YuanKey Laboratory of Laboratory Medical Diagnostics, Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing, P.R. China.
Junmei LiuCentral Laboratory of Yong Chuan Hospital, Chongqing Medical University, Chongqing, P.R. China.
Shifei YaoCentral Laboratory of Yong Chuan Hospital, Chongqing Medical University, Chongqing, P.R. China.
Yi ZhaoCentral Laboratory of Yong Chuan Hospital, Chongqing Medical University, Chongqing, P.R. China.
Min ChenCentral Laboratory of Yong Chuan Hospital, Chongqing Medical University, Chongqing, P.R. China.
Lianwen LiCentral Laboratory of Yong Chuan Hospital, Chongqing Medical University, Chongqing, P.R. China.
Lu LiuKey Laboratory of Laboratory Medical Diagnostics, Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing, P.R. China.
Beizhong LiuCentral Laboratory of Yong Chuan Hospital, Chongqing Medical University, Chongqing, P.R. China.
Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RAS-responsive element-binding protein 1 (RREB1) is a transcription factor that is implicated in RAS signaling and multiple tumors. However, the role of RREB1 in acute myeloid leukemia has not been studied. We found that RREB1 is overexpressed in AML patients and myeloid leukemia cell lines (NB4 and HL-60), and RREB1 expression was significantly decreased during granulocytic differentiation of myeloid leukemia cells induced by all-

Indexed as

Cell DifferentiationDNA-Binding ProteinsGene Knockdown TechniquesGranulocytesHL-60 CellsHumansLeukemia, Myeloid, AcuteMicroRNAsras ProteinsSignal TransductionTranscription FactorsTretinoinDNA-Binding ProteinsMicroRNAsMIRN145 microRNA, humanras ProteinsRREB1 protein, humanTranscription FactorsTretinoin

Identifiers

PMID30982491
PMCPMC7848438
OpenAlexW2937006451

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.