ArticleAutophagy2019
HIF1A and NFAT5 coordinate Na
Open access · hybridAbstract read
In one paragraph
Article in Autophagy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)Autophagy · 2021Guideline
- Piezo1 drives fibroblast activation in epidural fibrotic remodelling via the ET-1/HIF-1α pathway.Bone & joint research · 2026Article
- Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The effects of hypoxia inducible factor-1α in myeloid cells and a high-salt diet in a mouse model of orthodontic tooth movement.Korean journal of orthodontics · 2026Article
- Hypoxia inducible factor 1 subunit alpha mediates autophagy disorder of oral lichen planus by regulating lysosomal pathway.Frontiers in immunology · 2026Article
- Kidney immunology from pathophysiology to clinical translation.Nature reviews. Immunology · 2025Review
- NFAT5: a stress-related transcription factor with multiple functions in health and disease.Cell stress · 2025Review
- During high salt treatment myeloid p38α/MAPK fosters osteoclast activity and inflammatory macrophage responses promoting orthodontic tooth movement.Frontiers in immunology · 2025Article
- HES1 potentiates high salt stress response as an enhancer of NFAT5-DNA binding.Communications biology · 2024Article
- Placental growth factor mediates pathological uterine angiogenesis by activating the NFAT5-SGK1 signaling axis in the endometrium: implications for preeclampsia development.Biological research · 2024Article
- Rel Family Transcription Factor NFAT5 Upregulates COX2 via HIF-1α Activity in Ishikawa and HEC1a Cells.International journal of molecular sciences · 2024Article
- Advances in the study of autophagy in breast cancer.Breast cancer (Tokyo, Japan) · 2024Review
- Differential impact of high-salt levels in vitro and in vivo on macrophage core functions.Molecular biology reports · 2024Article
- Simultaneous Increases in Intracellular Sodium and Tonicity Boost Antimicrobial Activity of Macrophages.Cells · 2023Article
- Tissue Sodium Accumulation Induces Organ Inflammation and Injury in Chronic Kidney Disease.International journal of molecular sciences · 2023Review
- The role of the osmosensitive transcription factor NFAT5 in corneal edema resorption after injury.Experimental & molecular medicine · 2023Article
- The modulatory effect of high salt on immune cells and related diseases.Cell proliferation · 2022Review
- Mosaic theory revised: inflammation and salt play central roles in arterial hypertension.Cellular & molecular immunology · 2022Review
- Dihydroartemisinin ameliorates chronic nonbacterial prostatitis and epithelial cellular inflammation by blocking the E2F7/HIF1α pathway.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022Article
- Screening of a novel autophagy-related prognostic signature and therapeutic targets in hepatocellular carcinoma.Journal of gastrointestinal oncology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 10 institutions in 4 countries.
Patrick NeubertInstitute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg , Regensburg , Germany.
Andrea WeichselbaumInstitute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg , Regensburg , Germany.
Carmen ReitingerInstitute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg , Regensburg , Germany.
Valentin SchatzInstitute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg , Regensburg , Germany.
Agnes SchröderInstitute of Orthodontics, University Hospital of Regensburg , Regensburg , Germany.
John R FerdinandMolecular Immunity Unit, Department of Medicine, MRC-Laboratory of Molecular Biology, University of Cambridge , Cambridge , UK.ORCID 0000-0003-0936-0128
Michaela SimonInstitute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg , Regensburg , Germany.ORCID 0000-0002-8166-7178
Anna-Lorena BärInstitute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg , Regensburg , Germany.
Christoph BrochhausenInstitute of Pathology, University of Regensburg , Regensburg , Germany.
Roman G GerlachProject Group 5, Robert Koch Institute , Wernigerode , Germany.ORCID 0000-0002-5718-4758
Stefan TomiukMiltenyi Biotec GmbH , Bergisch Gladbach , Germany.
Karin HammerDepartment of Internal Medicine II, University Hospital of Regensburg and University of Regensburg , Regensburg , Germany.
Stefan WagnerDepartment of Internal Medicine II, University Hospital of Regensburg and University of Regensburg , Regensburg , Germany.ORCID 0000-0002-9471-1166
Ger van ZandbergenDivision of Immunology, Paul-Ehrlich-Institute , Langen , Germany.
Katrina J BingerDepartment of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne , Parkville , Australia.ORCID 0000-0003-1139-3308
Dominik N MüllerExperimental and Clinical Research Center, a joint cooperation of Max-Delbrück Center for Molecular Medicine and Charité-Universitätsmedizin Berlin , Berlin , Germany.
Kento KitadaCardiovascular and Metabolic Disorders, Duke-NUS Medical School , Singapore.
Menna R ClatworthyMolecular Immunity Unit, Department of Medicine, MRC-Laboratory of Molecular Biology, University of Cambridge , Cambridge , UK.ORCID 0000-0002-3340-9828
Christian KurtsInstitute of Experimental Immunology, University of Bonn , Bonn , Germany.
Jens TitzeCardiovascular and Metabolic Disorders, Duke-NUS Medical School , Singapore.ORCID 0000-0001-8463-8404
Zeinab AbdullahInstitute of Experimental Immunology, University of Bonn , Bonn , Germany.
Jonathan JantschInstitute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg , Regensburg , Germany.
University Hospital Regensburg · DEDuke-NUS Medical School · SGMRC Laboratory of Molecular Biology · GBUniversity of Bonn · DEMax Delbrück Center · DEMiltenyi Biotec (Germany) · DEPaul Ehrlich Institut · DERobert Koch Institute · DEThe University of Melbourne · AUUniversity of Regensburg · DE
Funding
Department of Health
Abstract
Infection and inflammation are able to induce diet-independent Na
Indexed as
AnimalsAutophagosomesAutophagyEscherichia coliHomeodomain ProteinsHydrogen-Ion ConcentrationHypoxia-Inducible Factor 1, alpha SubunitInflammationLysosomesMacrophagesMannitolMiceMicroscopy, Electron, TransmissionNitric Oxide Synthase Type IIOligonucleotide Array Sequence AnalysisOsmotic PressureHif1a protein, mouseHomeodomain ProteinsHypoxia-Inducible Factor 1, alpha SubunitMannitolmTOR protein, mouseNfat5 protein, mouseNitric Oxide Synthase Type IINos2 protein, mousePhox2a protein, mouseProto-Oncogene Proteins c-aktReactive Oxygen SpeciesSodiumTOR Serine-Threonine KinasesTranscription FactorsAutophagycell-autonomous immunitymacrophagesaltsodium
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.