Evidence map›Paper›PMID 30982333›Full record

ArticleThe British journal of radiology2019

Cyclo-oxygenase-2 expression is associated with mean standardised uptake value on 18F-Fluorodeoxyglucose positron emission tomography in oesophageal adenocarcinoma.

Kieran G Foley, Adam Christian, James Peaker, Christopher Marshall, Emiliano Spezi, Howard Kynaston, Ashley Roberts

Open access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kieran G Foley1 Division of Cancer & Genetics, School of Medicine, Cardiff University , Cardiff , UK.
Adam Christian2 Department of Pathology, University Hospital of Wales , Cardiff , UK.
James Peaker2 Department of Pathology, University Hospital of Wales , Cardiff , UK.
Christopher Marshall3 Wales Research and Diagnostic Positron Emission Tomography Imaging Centre (PETIC), Cardiff University , Cardiff , UK.
Emiliano Spezi4 School of Engineering, Cardiff University , Cardiff , UK.
Howard Kynaston1 Division of Cancer & Genetics, School of Medicine, Cardiff University , Cardiff , UK.
Ashley Roberts5 Department of Radiology, University Hospital of Wales , Cardiff , UK.
Cardiff University · GBUniversity Hospital of Wales · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis pilot study investigated the association of four PET image features and cyclo-oxygenase-2 (COX-2) expression in patients with oesophageal adenocarcinoma. The prognostic significance of these biomarkers was also assessed.

methods50 consecutive patients [median age = 68 (range 47 - 84), males = 45) with oesophageal adenocarcinoma had PET/CT staging between January 2011 and July 2015. The maximum and mean standardised uptake values (SUV

results32 tumours (64.0%) were COX-2 positive. There was a significant association between SUV

conclusionsThis study investigated the association between PET image features and COX-2 expression in oesophageal adenocarcinoma. The preliminary results signal that a combination of TLG (calculated as product of MTV and SUV ADVANCES IN KNOWLEDGE: Mean standardised uptake value (SUV

Indexed as

AdenocarcinomaAgedAged, 80 and overBiomarkersCyclooxygenase 2Esophageal NeoplasmsEsophagusFemaleFluorodeoxyglucose F18HumansKaplan-Meier EstimateMaleMiddle AgedPilot ProjectsPositron-Emission TomographyRadiopharmaceuticalsBiomarkersCyclooxygenase 2Fluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID30982333
PMCPMC6636260
OpenAlexW2937157080

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.