Evidence map›Paper›PMID 30982323›Full record

ReviewThe British journal of radiology2019

Preclinical neuroimaging of gene-environment interactions in psychiatric disease.

Sue Y Yi, Brian R Barnett, John-Paul J Yu

Open access · greenAbstract readReview
In one paragraph

Review in The British journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Effects of Psilocybin on Mouse Brain Microstructure.AJNR. American journal of neuroradiology · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sue Y Yi1Neuroscience Training Program, University of Wisconsin-Madison, Wisconsin Institutes for Medical Research, Madison, USA.
Brian R Barnett1Neuroscience Training Program, University of Wisconsin-Madison, Wisconsin Institutes for Medical Research, Madison, USA.
John-Paul J Yu1Neuroscience Training Program, University of Wisconsin-Madison, Wisconsin Institutes for Medical Research, Madison, USA.ORCID http://orcid.org/0000-0003-1878-052X
University of Wisconsin–Madison · US

Funding

INTEGRATED TRAINING FOR PHYSICIAN-SCIENTISTST32GM008692 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BURKARD, MARK E · 1998 to 2020
$10.3M
NIGMS NIH HHS T32 GM008692
6 · The paper itself

Abstract

Psychiatric disease is one of the leading causes of disability worldwide. Despite the global burden and need for accurate diagnosis and treatment of mental illness, psychiatric diagnosis remains largely based on patient-reported symptoms, allowing for immense symptomatic heterogeneity within a single disease. In renewed efforts towards improved diagnostic specificity and subsequent evaluation of treatment response, a greater understanding of the underlying of the neuropathology and neurobiology of neuropsychiatric disease is needed. However, dissecting these mechanisms of neuropsychiatric illness in clinical populations are problematic with numerous experimental hurdles limiting hypothesis-driven studies including genetic confounds, variable life experiences, different environmental exposures, therapeutic histories, as well as the inability to investigate deeper molecular changes

Indexed as

Gene-Environment InteractionBrainHumansMagnetic Resonance ImagingMental DisordersNeuroimaging

Identifiers

PMID30982323
PMCPMC6732909
OpenAlexW2936495870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.