Evidence map›Paper›PMID 30982188›Full record

ReviewEnvironmental science and pollution research international2020

Synthetic melanin nanoparticles as peroxynitrite scavengers, photothermal anticancer and heavy metals removal platforms.

Shaimaa Maher, Marwa Mahmoud, Moustafa Rizk, Haitham Kalil

Abstract readReview
PubMed Publisher
In one paragraph

Review in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Journal of Zhejiang University. Science. B · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Advances in nanotechnology, nanopollution, nanotoxicology, and nanomedicine.Environmental science and pollution research international · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shaimaa MaherDepartment of Chemistry, College of Science, Cleveland State University, Cleveland, OH, 44115, USA.
Marwa MahmoudDepartment of Science and Mathematics, Faculty of Petroleum and Mining Engineering, Suez University, Suez, Egypt.
Moustafa RizkDepartment of Chemistry, Faculty of Science and Arts, Najran University, Sharourah, Najran, Saudi Arabia.
Haitham KalilDepartment of Chemistry, College of Science, Cleveland State University, Cleveland, OH, 44115, USA. kalilha@mountunion.edu.ORCID http://orcid.org/0000-0002-5140-1504

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanin is a ubiquitous natural polyphenolic pigment with versatile applications including physiological functions. This polymeric material is found in a diversity of living organisms from bacteria to mammals. The biocompatibility and thermal stability of melanin nanoparticles make them good candidates to work as free radical scavengers and photothermal anticancer substrates. Research studies have identified melanin as an antioxidative therapeutic agent and/or reactive oxygen species (ROS) scavenger that includes neutralization of peroxynitrite. In addition, melanin nanoparticles have emerged as an anticancer photothermal platform that has the capability to kill cancer cells. Recently, melanin nanoparticles have been successfully used as chelating agents to purify water from heavy metals, such as hexavalent chromium. This review article highlights some selected aspects of cutting-edge melanin applications. Herein, we will refer to the recent literature that addresses melanin nanoparticles and its useful physicochemical properties as a hot topic in biomaterial science. It is expected that the techniques of Dynamic Light Scattering (DLS), Scanning Electron Microscopy (SEM), and time-resolved Electron Paramagnetic Resonance (EPR) will have a strong impact on the full characterization of melanin nanoparticles and the subsequent exploration of their physiological and chemical mechanisms.

Indexed as

Metals, HeavyNanoparticlesAnimalsMelaninsPeroxynitrous AcidPolymersMelaninsMetals, HeavyPeroxynitrous AcidPolymersEumelaninHeavy metals removal agentMelanin nanoparticlesPeroxynitrite scavengersPhotothermal anticancer platformROS

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.