Evidence map›Paper›PMID 30982109›Full record

SynthesisKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2019

Meniscal allograft transplantation after meniscectomy: clinical effectiveness and cost-effectiveness.

Norman Waugh, Hema Mistry, Andrew Metcalfe, Emma Loveman, Jill Colquitt, Pamela Royle, Nick A Smith, Tim Spalding

Open access · hybridAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. The Current State of Meniscus Replacements.Current reviews in musculoskeletal medicine · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Autologous semitendinosus tendon graft could function as a meniscal transplant.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022
    Article
  11. Article
  12. An increasing trend of the number of meniscus allograft transplantation in Korea.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. MR variability of collagen meniscal implant remodelling in patients with good clinical outcome.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Norman WaughDivision of Health Sciences, Warwick Medical School, Gibbet Hill Campus, University of Warwick, Coventry, CV4 7AL, UK. norman.waugh@warwick.ac.uk.ORCID http://orcid.org/0000-0003-0934-4961
Hema MistryDivision of Health Sciences, Warwick Medical School, Gibbet Hill Campus, University of Warwick, Coventry, CV4 7AL, UK.ORCID http://orcid.org/0000-0002-5023-1160
Andrew MetcalfeWarwick Clinical Trials Unit, University of Warwick, Coventry, UK.ORCID http://orcid.org/0000-0002-4515-8202
Emma LovemanEffective Evidence, Waterlooville, Hampshire, UK.ORCID http://orcid.org/0000-0001-8226-2634
Jill ColquittEffective Evidence, Waterlooville, Hampshire, UK.ORCID http://orcid.org/0000-0001-5962-2689
Pamela RoyleDivision of Health Sciences, Warwick Medical School, Gibbet Hill Campus, University of Warwick, Coventry, CV4 7AL, UK.ORCID http://orcid.org/0000-0001-5175-1005
Nick A SmithDepartment of Orthopaedics, University Hospitals Coventry and Warwickshire, Coventry, UK.
Tim SpaldingDepartment of Orthopaedics, University Hospitals Coventry and Warwickshire, Coventry, UK.
University of Warwick · GBUniversity Hospitals Coventry and Warwickshire NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the clinical effectiveness and cost-effectiveness of meniscal allograft transplantation (MAT) after meniscal injury and subsequent meniscectomy.

methodsSystematic review of clinical effectiveness and cost-effectiveness analysis.

resultsThere is considerable evidence from observational studies, of improvement in symptoms after meniscal allograft transplantation, but we found only one small pilot trial with a randomised comparison with a control group that received non-surgical care. MAT has not yet been proven to be chondroprotective. Cost-effectiveness analysis is not possible due to a lack of data on the effectiveness of MAT compared to non-surgical care.

conclusionThe benefits of MAT include symptomatic relief and restoration of at least some previous activities, which will be reflected in utility values and hence in quality-adjusted life years, and in the longer term, prevention or delay of osteoarthritis, and avoidance or postponement of some knee replacements, with resulting savings. It is likely to be cost-effective, but this cannot be proven on the basis of present evidence. LEVEL OF EVIDENCE: IV.

Indexed as

Cost-Benefit AnalysisGraft SurvivalHumansMeniscectomyMenisci, TibialOsteoarthritis, KneePostoperative ComplicationsQuality of LifeReoperationReturn to SportTransplantation, HomologousCost-effectivenessMeniscal allograft transplantation

Identifiers

PMID30982109
PMCPMC6541576
OpenAlexW2939925688

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.