Observational studyJournal of clinical hypertension (Greenwich, Conn.)2019
Hypertension-induced subclinical vascular and cognitive changes are reversible-An observational cohort study.
Observational study in Journal of clinical hypertension (Greenwich, Conn.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Reply to letter: Reversibility of hypertension-induced subclinical vascular changes: Do the new ACC/AHA 2017 blood pressure guidelines and heart rate changes make a difference?Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Observational
- Reversibility of hypertension-induced subclinical vascular changes: Do the new ACC/AHA 2017 blood pressure guidelines and heart rate changes make a difference?Journal of clinical hypertension (Greenwich, Conn.) · 2019Article
- Hypertension-induced subclinical vascular and cognitive changes are reversible-An observational cohort study.Journal of clinical hypertension (Greenwich, Conn.) · 2019Observational
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13 authors.
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Abstract
Beside the well-known complications of poorly controlled, long-standing hypertension, milder abnormalities induced by early-stage hypertension have also been described. In our study, the authors examined the reversibility of changes induced by early-stage hypertension. The authors performed laboratory testing, ambulatory blood pressure monitoring, carotid intima-media thickness (IMT) measurement, evaluation of stiffness parameters, assessment of various cardiac and cerebral hemodynamic parameters during head-up tilt table (HUTT) testing, and neuropsychological examinations in 49 recently diagnosed hypertensive patients. Following baseline assessment, antihypertensive therapy was commenced. After one year of therapy, lower IMT values were found. Pulse wave velocity showed a borderline significant decrease. During HUTT, several hemodynamic parameters improved. The patients performed better on neuropsychological testing and reached significantly lower scores on questionnaires evaluating anxiety. The present study shows that early vascular changes and altered cognitive function observed in newly diagnosed hypertensive patients may improve with promptly initiated antihypertensive management.
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