ReviewCurrent treatment options in gastroenterology2019
Infections in Cirrhosis.
Review in Current treatment options in gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Clinical impact and disparities in mortality and antimicrobial resistance between Gram-negative and Gram-positive bacteria in cirrhotic abdominal infections: a meta-analysis.Frontiers in medicine · 2025Pooled it
- Pneumococcal Vaccine for Adults Aged ≥19 Years: Recommendations of the Advisory Committee on Immunization Practices, United States, 2023.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2023Guideline
- Antibiotics for prophylaxis of spontaneous bacterial peritonitis: systematic review & Bayesian network meta-analysis.Hepatology international · 2020Pooled it
- Safety and Efficacy of Dapagliflozin in Recurrent Ascites: A Pilot Study.Digestive diseases and sciences · 2025Trial
- Impact of bacterial infection on native liver survival in children with cirrhosis due to biliary atresia.Clinical and experimental pediatrics · 2026Article
- Diagnostic Accuracy of Leucocyte Esterase Reagent Strips for Spontaneous Bacterial Peritonitis in Cirrhosis With Ascites.Health science reports · 2026Article
- Comparison ofGastroenterology research · 2026Article
- Impact of cirrhosis on patients admitted with an exacerbation of acute chronic obstructive pulmonary disease: a nationwide analysis.Proceedings (Baylor University. Medical Center) · 2026Article
- Gonococcal Peritonitis Complicated by Intraperitoneal Abscess and Pleural Empyema: A Case Report.Clinical case reports · 2026Article
- FIB-4 index associated with mortality risk of patients with systemic lupus erythematosus: a large retrospective cohort study.Archives of medical science : AMS · 2026Article
- Myeloid cells in chronic liver inflammation.Cellular & molecular immunology · 2025Review
- Higher NLR Values Can Predict Gram-Negative Spontaneous Bacterial Peritonitis and a High In-Hospital Mortality Rate in Patients with Spontaneous Bacterial Peritonitis.Life (Basel, Switzerland) · 2025Article
- A novel risk-predicted nomogram for acute kidney injury progression in decompensated cirrhosis: a double-center study in Vietnam.International urology and nephrology · 2025Article
- Predominant Gram-Positive Etiology May Be Associated with a Lower Mortality Rate but with Higher Antibiotic Resistance in Spontaneous Bacterial Peritonitis: A 7-Year Study in a Tertiary Center in Romania.Life (Basel, Switzerland) · 2025Article
- Fluoroquinolones for the Prophylaxis of Spontaneous Bacterial Peritonitis in Patients with Liver Cirrhosis: Are They Losing Ground?Life (Basel, Switzerland) · 2025Review
- Bacterial resistance profile and its association with poor outcome among cirrhosis patients attending a tertiary care referral center in northern India.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025Observational
- COVID-19 Vaccination in Liver Cirrhosis: Safety and Immune and Clinical Responses.GE Portuguese journal of gastroenterology · 2024Article
- Article
- Expert consensus on the diagnosis and treatment of end-stage liver disease complicated by infections.Hepatology international · 2024Review
- Cirrhosis with COVID-19: Just another infection or something more to it?JGH open : an open access journal of gastroenterology and hepatology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewPatients with cirrhosis are at high risk of developing serious infections. Bacterial infections remain the most common cause of morbidity and mortality in these patients. This review is focused on the prevalence of infections in those with cirrhosis, including multidrug-resistant (MDR) pathogens, pathogenesis of infection-related acute-on-chronic liver failure (ACLF), current treatment recommendations, and prophylactic strategies in patients with cirrhosis. RECENT
findingsRecent epidemiological studies have noted an emerging prevalence of MDR bacterial infections and associated with poor prognosis, and a high rate of treatment failure and mortality. Therefore, new recommendations on empirical antibiotic use based on epidemiological data have been developed in order to improve outcomes. Spontaneous bacterial peritonitis (SBP) and urinary tract infection (UTI) are the most frequent infections followed by pneumonia, cellulitis, and bacteremia, while pneumonia carries the highest risk of mortality. The incidence of MDR bacterial infections has been increasing, especially in healthcare-associated settings. Second infections that develop during hospitalization, multiple organ failures, and high MELD score are associated with poor survival. Preventive measures, early diagnosis, and adequate treatment of infections are essential key concepts in minimizing morbidity and mortality in patients with cirrhosis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.