Evidence map›Paper›PMID 30980291›Full record

ReviewAnnals of biomedical engineering2019

Microfluidics-Based Organism Isolation from Whole Blood: An Emerging Tool for Bloodstream Infection Diagnosis.

Alison Burklund, John X J Zhang

Abstract readReview
In one paragraph

Review in Annals of biomedical engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Molecular Methodologies for Improved Polymicrobial Sepsis Diagnosis.International journal of molecular sciences · 2022
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alison BurklundThayer School of Engineering at Dartmouth, 14 Engineering Drive, Hanover, NH, 03755, USA.
John X J ZhangThayer School of Engineering at Dartmouth, 14 Engineering Drive, Hanover, NH, 03755, USA. john.zhang@dartmouth.edu.

Funding

Implantable Cardiac Power Generation Using Flexible 3D Porous Thin FilmsR01HL137157 · NHLBI · DARTMOUTH COLLEGE · PI ZHANG, XIAOJING · 2016 to 2020
$2.2M
Detection of CarcinomasR01CA139070 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI ZHANG, XIAOJING · 2011 to 2013
$925k
NCI NIH HHS R01 CA139070NHLBI NIH HHS R01 HL137157NIH Office of the Director 1R01OD022910-01
6 · The paper itself

Abstract

The diagnosis of bloodstream infections presents numerous challenges, in part, due to the low concentration of pathogens present in the peripheral bloodstream. As an alternative to existing time-consuming, culture-based diagnostic methods for organism identification, microfluidic devices have emerged as rapid, high-throughput and integrated platforms for bacterial and fungal enrichment, detection, and characterization. This focused review serves to highlight and compare the emerging microfluidic platforms designed for the isolation of sepsis-causing pathogens from blood and suggest important areas for future research.

Indexed as

Microfluidic Analytical TechniquesBacteriaHumansMicrofluidicsPoint-of-Care TestingSepsisHematologyInfectious disease diagnosticsLab-on-a-chipMicrofluidicsSepsis

Identifiers

PMID30980291
PMCPMC6687464

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.