Evidence map›Paper›PMID 30980283›Full record

ArticleTranslational stroke research2019

Obesity Paradox in Ischemic Stroke: Clinical and Molecular Insights.

Emilio Rodríguez-Castro, Manuel Rodríguez-Yáñez, Susana Arias-Rivas, María Santamaría-Cadavid, Iria López-Dequidt, Pablo Hervella, Miguel López, Francisco Campos, Tomás Sobrino, José Castillo

Abstract read
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In one paragraph

Article in Translational stroke research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Impact of Obesity-Induced Inflammation on Cardiovascular Diseases (CVD).International journal of molecular sciences · 2021
    Pooled it
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  17. Heliyon · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Emilio Rodríguez-CastroStroke Unit, Department of Neurology, Hospital Clínico Universitario, Santiago de Compostela, Spain.
Manuel Rodríguez-YáñezStroke Unit, Department of Neurology, Hospital Clínico Universitario, Santiago de Compostela, Spain.
Susana Arias-RivasStroke Unit, Department of Neurology, Hospital Clínico Universitario, Santiago de Compostela, Spain.
María Santamaría-CadavidStroke Unit, Department of Neurology, Hospital Clínico Universitario, Santiago de Compostela, Spain.
Iria López-DequidtStroke Unit, Department of Neurology, Hospital Clínico Universitario, Santiago de Compostela, Spain.
Pablo HervellaClinical Neurosciences Research Laboratory, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain.
Miguel LópezNeurObesity Group, Department of Physiology, CIMUS, Universidade de Santiago de Compostela and Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain.
Francisco CamposClinical Neurosciences Research Laboratory, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain.
Tomás SobrinoClinical Neurosciences Research Laboratory, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain. tomas.sobrino.moreiras@sergas.es.ORCID 0000-0002-9760-8690
José CastilloClinical Neurosciences Research Laboratory, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain. jose.castillo.sanchez@sergas.es.
Complejo Hospitalario Universitario de Santiago · ESInstituto de Investigación Sanitaria de Santiago · ESUniversidade de Santiago de Compostela · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has recently emerged the concept of "obesity paradox," a term used to describe the unexpected improved prognosis and lower mortality rates found in several diseases in patients with higher body weight. Concerning stroke, few clinical studies have assessed this obesity paradox showing contradictory results. Therefore, our aim was to compare clinical evolution and inflammatory balance of obese and non-obese patients after ischemic stroke. We designed a prospective case-control study in patients with acute ischemic stroke categorized into obese (body mass index, BMI ≥ 30 kg/m

Indexed as

AgedAged, 80 and overBody WeightBrain IschemiaCase-Control StudiesFemaleHumansInflammationInterleukin-10Interleukin-6Logistic ModelsMaleMiddle AgedObesityPrognosisProspective StudiesInterleukin-10Interleukin-6InflammationIschemic strokeObesityOutcomePrognosis

Identifiers

PMID30980283
OpenAlexW2935788522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.