Observational studyClinical infectious diseases : an official publication of the Infectious Diseases Society of America2019
Multidrug-resistant Organisms in Hospitals: What Is on Patient Hands and in Their Rooms?
Observational study in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The challenge of preventing and containing outbreaks of multidrug-resistant organisms and Candida auris during the coronavirus disease 2019 pandemic: report of a carbapenem-resistant Acinetobacter baumannii outbreak and a systematic review of the literature.Antimicrobial resistance and infection control · 2022Pooled it
- Effectiveness of a Multicomponent Intervention to Reduce Multidrug-Resistant Organisms in Nursing Homes: A Cluster Randomized Clinical Trial.JAMA network open · 2021Trial
- Assessment of the role of handwash basins in the airborne transmission of multi-drug-resistant organisms in clinical and non-clinical settings.The Journal of hospital infection · 2026Article
- Environmental reservoirs of carbapenem-resistant organisms in the intensive care unit: a multicenter longitudinal study in two middle-income country hospitals.Antimicrobial resistance and infection control · 2026Article
- Diagnostic advantage of droplet digital PCR over blood culture in sepsis: a retrospective study of 115 patients.European journal of medical research · 2026Article
- What are the microbial burden and potential pathogens on hospital surfaces before and after cleaning?Frontiers in microbiology · 2026Article
- Determinants of multidrug-resistant urinary tract infections: A retrospective cross-sectional study from a tertiary care hospital in southern Bangladesh.PLOS global public health · 2026Article
- Article
- S2k Guideline: Hygienic requirements for patient beds, bed linen, bed accessories and personal protection when handling beds.GMS hygiene and infection control · 2026Article
- S2k Guideline: Hygienic requirements for patient beds, bed linen, bed accessories and personal protection when handling beds.GMS hygiene and infection control · 2025Article
- A Multidisciplinary-Based and Bundle Intervention for Controlling Carbapenem-Resistant Organisms in Neurosurgery.Infection and drug resistance · 2025Article
- Expanding subcutaneous mass on the scalp of an immunocompromised woman.Skin health and disease · 2024Article
- Hand and environmental hygiene: respective roles for MRSA, multi-resistant gram negatives, Clostridioides difficile, and Candida spp.Antimicrobial resistance and infection control · 2024Review
- In Silico Drug Repurposing Endorse Amprenavir, Darunavir and Saquinavir to Target Enzymes of Multidrug Resistant UropathogenicIndian journal of microbiology · 2024Article
- High clonal diversity of Staphylococcus aureus isolates from children's playgrounds in Hungary.Scientific reports · 2024Article
- Microbiological Analysis of Surgeons' Hands in a Public Hospital in São Luis, Maranhão State, Brazil: A Cross-Sectional Study.Microorganisms · 2023Article
- Mitigating hospital-onsetInfection control and hospital epidemiology · 2023Article
- Multidrug-resistant bacteria in the grey shades of immunosuppression.Intensive care medicine · 2023Article
- Environmental chamber studies of eye and respiratory irritation from use of a peracetic acid-based hospital surface disinfectant.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- Efficacy and Safety of Fecal Microbiota Transplantation for Clearance of Multidrug-Resistant Organisms under Multiple Comorbidities: A Prospective Comparative Trial.Biomedicines · 2022Article
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Abstract
backgroundThe impact of healthcare personnel hand contamination in multidrug-resistant organism (MDRO) transmission is important and well studied; however, the role of patient hand contamination needs to be characterized further.
methodsPatients from 2 hospitals in southeast Michigan were recruited within 24 hours of arrival to their room and followed prospectively using microbial surveillance of nares, dominant hand, and 6 high-touch environmental surfaces. Sampling was performed on admission, days 3 and 7, and weekly until discharge. Paired samples of methicillin-resistant Staphylococcus aureus (MRSA) isolated from the patients' hand and room surfaces were evaluated for relatedness using pulsed-field gel electrophoresis and staphylococcal cassette chromosome mec, and Panton-Valentine leukocidin typing.
resultsA total of 399 patients (mean age, 60.8 years; 49% male) were enrolled and followed for 710 visits. Fourteen percent (n = 56/399) of patients were colonized with an MDRO at baseline; 10% (40/399) had an MDRO on their hands. Twenty-nine percent of rooms harbored an MDRO. Six percent (14/225 patients with at least 2 visits) newly acquired an MDRO on their hands during their stay. New MDRO acquisition in patients occurred at a rate of 24.6/1000 patient-days, and in rooms at a rate of 58.6/1000 patient-days. Typing demonstrated a high correlation between MRSA on patient hands and room surfaces.
conclusionsOur data suggest that patient hand contamination with MDROs is common and correlates with contamination on high-touch room surfaces. Patient hand hygiene protocols should be considered to reduce transmission of pathogens and healthcare-associated infections.
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