ArticleScientific reports2019
Buffalo milk transcriptome: A comparative analysis of early, mid and late lactation.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Weighted gene co-expression network analysis identifies modules and functionally enriched pathways in the lactation process.Scientific reports · 2021Pooled it
- Persistent effects of neonatal diarrhea on Holstein dairy cow lactation performance through multiple parities.Journal of animal science · 2026Article
- Comparative Single-Cell Transcriptomic Landscape Reveals the Regulatory Mechanisms of Lactation during Selective Breeding in Asian Water Buffalo.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Transcriptomic profiling of milk fat globules in cows with different β-casein genotypes.Scientific reports · 2025Article
- Transcriptomic and Proteomic Insights Into Buffalo Milk Fat Synthesis and the Role of IGFBP4 in BMECs.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- A Spatiotemporal Atlas of the Gut Microbiota inBiology · 2025Article
- Proteomic analysis of Buffalo milk somatic cells reveals metabolomic and immunological transitions during early lactation.Scientific reports · 2025Article
- Characterization of mammary glands and milk fat globule transcripts in lactating buffalo and goats.Food chemistry. Molecular sciences · 2025Article
- Molecular Characteristics and Role of BuffaloGenes · 2025Article
- BuffExDb: web-based tissue-specific gene expression resource for breeding and conservation programmes in Bubalus bubalis.Database : the journal of biological databases and curation · 2025Article
- Cytokine interactions and chemokine dysregulations in mastitis immunopathogenesis: insights from transcriptomic profiling of milk somatic cells in tropical Sahiwal (Frontiers in immunology · 2025Article
- Transcriptomic analysis reveals molecular insights into lactation dynamics in Jakhrana goat mammary gland.BMC genomics · 2024Article
- Mammary fat globules as a source of mRNA to model alterations in the expression of some milk component genes during lactation in bovines.BMC veterinary research · 2024Article
- Role of Different Members of theGenes · 2023Article
- Transcriptomic profiles of the ruminal wall in Italian Mediterranean dairy buffaloes fed green forage.BMC genomics · 2023Article
- Nutritional Modulation, Gut, and Omics Crosstalk in Ruminants.Animals : an open access journal from MDPI · 2022Review
- Transcriptomic in silico analysis of bovine Escherichia coli mastitis highlights its immune-related expressed genes as an effective biomarker.Journal, genetic engineering & biotechnology · 2021Article
- Characterization and comparative analysis of transcriptional profiles of porcine colostrum and mature milk at different parities.BMC genomic data · 2021Article
- Article
- SNPs in Mammary Gland Epithelial Cells Unraveling Potential Difference in Milk Production Between Jersey and Kashmiri Cattle Using RNA Sequencing.Frontiers in genetics · 2021Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The expression of genes and their regulation during lactation in buffaloes remains less understood. To understand the interplay of various genes and pathways, the milk transcriptome from three lactation stages of Murrah buffalo was analyzed by RNA sequencing. The filtered reads were mapped to the Bubalus bubalis as well as Bos taurus reference assemblies. The average mapping rate to water buffalo and Btau 4.6 reference sequence, was 75.5% and 75.7% respectively. Highly expressed genes (RPKM > 3000), throughout lactation included CSN2, CSN1S1, CSN3, LALBA, SPP1 and TPT1. A total of 12833 transcripts were common across all the stages, while 271, 205 and 418 were unique to early, mid and late lactation respectively. Majority of the genes throughout lactation were linked to biological functions like protein metabolism, transport and immune response. A discernible shift from metabolism in early stage to metabolism and immune response in mid stage, and an increase in immune response functions in late lactation was observed. The results provide information of candidate genes and pathways involved in the different stages of lactation in buffalo. The study also identified 14 differentially expressed and highly connected genes across the three lactation stages, which can be used as candidates for future research.
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