Evidence map›Paper›PMID 30979834›Full record

ArticleApplied and environmental microbiology2019

Reversible Gene Expression Control in Yersinia pestis by Using an Optimized CRISPR Interference System.

Tong Wang, Min Wang, Qingwen Zhang, Shiyang Cao, Xiang Li, Zhizhen Qi, Yafang Tan, Yang You, Yujing Bi, Yajun Song and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Plague vaccines: new developments in an ongoing search.Applied microbiology and biotechnology · 2021
    Review
  9. Review
  10. Article
  11. Deliberate release: Plague - A review.Journal of biosafety and biosecurity · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Tong WangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Min WangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Qingwen ZhangKey Laboratory for Plague Prevention and Control of Qinghai Province 2017-ZJ-Y15, Institute for Endemic Disease Prevention and Control of Qinghai Province, Xining, China.
Shiyang CaoState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Xiang LiKey Laboratory for Plague Prevention and Control of Qinghai Province 2017-ZJ-Y15, Institute for Endemic Disease Prevention and Control of Qinghai Province, Xining, China.
Zhizhen QiKey Laboratory for Plague Prevention and Control of Qinghai Province 2017-ZJ-Y15, Institute for Endemic Disease Prevention and Control of Qinghai Province, Xining, China.
Yafang TanState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Yang YouState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Yujing BiState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Yajun SongState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.ORCID 0000-0002-6628-2747
Ruifu YangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China ruifuyang@gmail.com zmduams@163.com.
Zongmin DuState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China ruifuyang@gmail.com zmduams@163.com.
Institute of Microbiology · CNQinghai Institute for Endemic Diease Prevention and Control · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many genes in the bacterial pathogen

Indexed as

Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsGene ExpressionGene Knockdown TechniquesStreptococcus pyogenesYersinia pestisCRISPRigene knockdownYersinia pestis

Identifiers

PMID30979834
PMCPMC6544824
OpenAlexW2939308373

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.