Evidence map›Paper›PMID 30979553›Full record

ArticleBiophysical journal2019

A Matched-Filter-Based Algorithm for Subcellular Classification of T-System in Cardiac Tissues.

Dylan F Colli, S Ryan Blood, Aparna C Sankarankutty, Frank B Sachse, Michael Frisk, William E Louch, Peter M Kekenes-Huskey

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Dylan F ColliDepartment of Chemistry, University of Kentucky, Lexington, Kentucky; Department of Chemical and Materials Engineering, University of Kentucky, Lexington, Kentucky. Electronic address: dfco222@g.uky.edu.
S Ryan BloodDepartment of Chemistry, University of Kentucky, Lexington, Kentucky; Department of Chemical and Materials Engineering, University of Kentucky, Lexington, Kentucky.
Aparna C SankarankuttyNora Eccles Harrison Cardiovascular Research and Training Institute & Department of Bioengineering, University of Utah, Salt Lake City, Utah.
Frank B SachseNora Eccles Harrison Cardiovascular Research and Training Institute & Department of Bioengineering, University of Utah, Salt Lake City, Utah.
Michael FriskInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway; K.G. Jebsen Cardiac Research Center and Center for Heart Failure Research, University of Oslo, Oslo, Norway.
William E LouchInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway; K.G. Jebsen Cardiac Research Center and Center for Heart Failure Research, University of Oslo, Oslo, Norway.
Peter M Kekenes-HuskeyDepartment of Chemistry, University of Kentucky, Lexington, Kentucky; Department of Chemical and Materials Engineering, University of Kentucky, Lexington, Kentucky.
University of Kentucky · USUniversity of Oslo · NOUniversity of Utah · US

Funding

The role of IKKß in linking obesity to adipose tissue inflammation and adipogeneP20GM103527 · NIGMS · UNIVERSITY OF KENTUCKY · PI MORRIS, ANDREW J · 2012 to 2017
$13.7M
Pilot Projects ProgramP30GM127211 · NIGMS · UNIVERSITY OF KENTUCKY · PI CASSIS, LISA A · 2018 to 2022
$5.7M
PROBING CELLULAR INTRACELLULAR CALCIUM SIGNALING AND SENSING THROUGH COMPUTATIONR35GM124977 · NIGMS · UNIVERSITY OF KENTUCKY · PI KEKENES-HUSKEY, PETER MICHAEL · 2017 to 2021
$1.8M
Cellular Remodeling in Heart Failure and after LVAD UnloadingR01HL132067 · NHLBI · UNIVERSITY OF UTAH · PI DRAKOS, STAVROS GEORGE, SACHSE, FRANK BERND · 2017 to 2020
$1.5M
NHLBI NIH HHS R01 HL132067NIGMS NIH HHS P20 GM103527NIGMS NIH HHS P30 GM127211NIGMS NIH HHS R35 GM124977
6 · The paper itself

Abstract

In mammalian ventricular cardiomyocytes, invaginations of the surface membrane form the transverse tubular system (T-system), which consists of transverse tubules (TTs) that align with sarcomeres and Z-lines as well as longitudinal tubules (LTs) that are present between Z-lines in some species. In many cardiac disease etiologies, the T-system is perturbed, which is believed to promote spatially heterogeneous, dyssynchronous Ca

Indexed as

AlgorithmsAnimalsHeart VentriclesImage Processing, Computer-AssistedIntracellular SpaceMyocytes, CardiacRats

Identifiers

PMID30979553
PMCPMC6486484
OpenAlexW2950501341

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.