Evidence map›Paper›PMID 30979276›Full record

ArticlePolymers2016

Hydrogel is Superior to Fibrin Gel as Matrix of Stem Cells in Alleviating Antigen-Induced Arthritis.

He Liu, Jianxun Ding, Chen Li, Chenyu Wang, Yinan Wang, Jincheng Wang, Fei Chang

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Mesenchymal Stem Cells-Involved Strategies for Rheumatoid Arthritis Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

He LiuDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun 130041, China. heliu@ciac.ac.cn.ORCID 0000-0001-7178-0276
Jianxun DingKey Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China. jxding@ciac.ac.cn.ORCID 0000-0002-5232-8863
Chen LiDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun 130041, China. evanlee1357@163.com.
Chenyu WangDepartment of orthopedics, Hallym University, Hallymdaehak-gil 1, Chuncheon 200-702, Korea. cathywang0111@hotmail.com.
Yinan WangAcademy of Translational Medicine, The First Bethune Hospital of Jilin University, Changchun 130021, China. wyn7859@aliyun.com.
Jincheng WangDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun 130041, China. jinchengwang@hotmail.com.
Fei ChangDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun 130041, China. ccfei_cn@hotmail.com.
Second Affiliated Hospital of Jilin University · CNChinese Academy of Sciences · CNFirst Bethune Hospital of Jilin University · CNHallym University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, therapy with bone marrow mesenchymal stem cells (BMMSCs) has been attempted to relieve rheumatoid arthritis (RA) and reconstruct cartilage injury. However, treatment has been unsuccessful in complete prevention of persistent cartilage destruction and resulted in inferior outcomes of cartilage regeneration. Scaffolds are an important construct in the field of cartilage tissue engineering, but their role in arthritis treatment has not yet been fully examined. Here, we transplanted two types of scaffold-assisted BMMSCs: fibrin gel- and poly(l-lactide-

Indexed as

bone marrow mesenchymal stem cellscartilage repairfibrin gelhydrogelovalbumin-induced arthritisrheumatoid arthritis

Identifiers

PMID30979276
PMCPMC6431989
OpenAlexW2346027324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.