Evidence map›Paper›PMID 30979252›Full record

ArticlePolymers2016

Biodegradable Polyphosphazene Based Peptide-Polymer Hybrids.

Anne Linhardt, Michael König, Wolfgang Schöfberger, Oliver Brüggemann, Alexander K Andrianov, Ian Teasdale

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Polyphosphazene immunoadjuvants: Historical perspective and recent advances.Journal of controlled release : official journal of the Controlled Release Society · 2021
    Review
  4. Biomedical applications of polyphosphazenes.Medical devices & sensors · 2020
    Article
  5. Review
  6. Stimuli-Responsive Phosphorus-Based Polymers.European journal of inorganic chemistry · 2019
    Review
  7. Degradable, Dendritic Polyols on a Branched Polyphosphazene Backbone.Industrial & engineering chemistry research · 2018
    Article
  8. A pH-sensitive Macromolecular Prodrug as TLR7/8 Targeting Immune Response Modifier.Chemistry (Weinheim an der Bergstrasse, Germany) · 2017
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Anne LinhardtInstitute of Polymer Chemistry, Johannes Kepler University Linz (JKU), Altenberger Straße 69, A-4040 Linz, Austria. anne.linhardt@jku.at.
Michael KönigInstitute of Polymer Chemistry, Johannes Kepler University Linz (JKU), Altenberger Straße 69, A-4040 Linz, Austria. michael.koenig@jku.at.
Wolfgang SchöfbergerInstitute of Organic Chemistry, Johannes Kepler University Linz (JKU), Altenberger Straße 69, A-4040 Linz, Austria. wolfgang.schoefberger@jku.at.ORCID 0000-0002-8055-8906
Oliver BrüggemannInstitute of Polymer Chemistry, Johannes Kepler University Linz (JKU), Altenberger Straße 69, A-4040 Linz, Austria. oliver.brueggemann@jku.at.
Alexander K AndrianovInstitute for Bioscience and Biotechnology Research, University of Maryland, 9600 Gudelsky Drive, Rockville, MD 20850, USA. andria1@umd.edu.ORCID 0000-0001-6186-6156
Ian TeasdaleInstitute of Polymer Chemistry, Johannes Kepler University Linz (JKU), Altenberger Straße 69, A-4040 Linz, Austria. ian.teasdale@jku.at.
Johannes Kepler University of Linz · ATInstitute for Bioscience and Biotechnology Research

Funding

Austrian Science Fund P 27410-N28Austrian Science Fund FWF P 28167Österreichische Forschungsförderungsgesellschaft FFGP13760002
6 · The paper itself

Abstract

A novel series of peptide based hybrid polymers designed to undergo enzymatic degradation is presented, via macrosubstitution of a polyphosphazene backbone with the tetrapeptide Gly-Phe-Leu-Gly. Further co-substitution of the hybrid polymers with hydrophilic polyalkylene oxide Jeffamine M-1000 leads to water soluble and biodegradable hybrid polymers. Detailed degradation studies, via

Indexed as

biodegradable polymerenzymatic degradationhydrolytic degradationimiquimod (R837)peptide-polymer conjugatePeptide-polymer hybridpolymer therapeuticspolyphosphazene

Identifiers

PMID30979252
PMCPMC6432119
OpenAlexW2337020968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.