ArticlePolymers2016
Fabrication of Nerve Growth Factor Encapsulated Aligned Poly(ε-Caprolactone) Nanofibers and Their Assessment as a Potential Neural Tissue Engineering Scaffold.
Article in Polymers, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Evaluation of a GDNF-eluting nanofibrous PCL conduit in a mouse model of peripheral nerve injury.RSC advances · 2026Article
- Synthesis and use of thermoplastic polymers for tissue engineering purposes.International journal of pharmaceutics: X · 2025Review
- An emulsion electrospun nanofibrous scaffold loaded with glial cell line-derived neurotrophic factor for nerve regeneration.Frontiers in cell and developmental biology · 2025Article
- Article
- Effective regeneration of rat sciatic nerve using nanofibrous scaffolds containing rat ADSCs with controlled release of rhNGF and melatonin molecules for the treatment of peripheral injury model.Regenerative therapy · 2023Article
- Ubiquitin ligase Triad1 promotes neurite outgrowth by inhibiting MDM2-mediated ubiquitination of the neuroprotective factor pleiotrophin.The Journal of biological chemistry · 2022Article
- Advances in Electrospun Hybrid Nanofibers for Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2022Review
- Effect of Ionic and Non-Ionic Surfactant on Bovine Serum Albumin Encapsulation and Biological Properties of Emulsion-Electrospun Fibers.Molecules (Basel, Switzerland) · 2022Article
- Optimal Morphometric Characteristics of a Tubular Polymeric Scaffold to Promote Peripheral Nerve Regeneration: A Scoping Review.Polymers · 2022Article
- Exosomes Derived From Umbilical Cord Mesenchymal Stem Cells Treat Cutaneous Nerve Damage and Promote Wound Healing.Frontiers in cellular neuroscience · 2022Article
- Electrospun core-shell nanofibers with encapsulated enamel matrix derivative for guided periodontal tissue regeneration.Dental materials journal · 2021Article
- Main Morphological Characteristics of Tubular Polymeric Scaffolds to Promote Peripheral Nerve Regeneration-A Scoping Review.Polymers · 2021Article
- Current Advances in 3D Tissue and Organ Reconstruction.International journal of molecular sciences · 2021Review
- 3D Electrospun Nanofiber-Based Scaffolds: From Preparations and Properties to Tissue Regeneration Applications.Stem cells international · 2021Review
- Designing Biomaterial Platforms for Cardiac Tissue and Disease Modeling.Advanced nanobiomed research · 2021Article
- Current progress in application of polymeric nanofibers to tissue engineering.Nano convergence · 2019Review
- New surgical meshes with patterned nanofiber mats.RSC advances · 2019Article
- Biomimetic cardiovascular platforms for in vitro disease modeling and therapeutic validation.Biomaterials · 2019Review
- Fabrication of Electrospun Polymer Nanofibers with Diverse Morphologies.Molecules (Basel, Switzerland) · 2019Review
- Polymeric Electrospun Fibrous Dressings for Topical Co-delivery of Acyclovir and Omega-3 Fatty Acids.Frontiers in bioengineering and biotechnology · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Peripheral nerve injury is a serious clinical problem to be solved. There has been no breakthrough so far and neural tissue engineering offers a promising approach to promote the regeneration of peripheral neural injuries. In this study, emulsion electrospinning technique was introduced as a flexible and promising technique for the fabrication of random (R) and aligned (A) Poly(ε-caprolactone) (PCL)-Nerve Growth Factor (NGF)&Bovine Serum Albumin (BSA) nanofibrous scaffolds [(R/A)-PCL-NGF&BSA], where NGF and BSA were encapsulated in the core while PCL form the shell. Random and aligned pure PCL, PCL-BSA, and PCL-NGF nanofibers were also produced for comparison. The scaffolds were characterized by Field Emission Scanning Electron Microscopy (FESEM) and water contact angle test. Release study showed that, with the addition of stabilizer BSA, a sustained release of NGF from emulsion electrospun PCL nanofibers was observed over 28 days. [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.