Evidence map›Paper›PMID 30979130›Full record

ArticlePolymers2016

l-Cystine-Crosslinked Polypeptide Nanogel as a Reduction-Responsive Excipient for Prostate Cancer Chemotherapy.

Liang He, Di Li, Zhongtang Wang, Weiguo Xu, Jixue Wang, Hui Guo, Chunxi Wang, Jianxun Ding

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Redox-Responsive Drug Delivery Systems: A Chemical Perspective.Nanomaterials (Basel, Switzerland) · 2022
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Liang HeDepartment of Urology, the First Hospital of Jilin University, Changchun 130021, China. lianghe9278@126.com.
Di LiKey Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China. lidi@ciac.ac.cn.
Zhongtang WangDepartment of Radiation Oncology, Shandong Cancer Hospital and Institute, Jinan 250117, China. zhongtangw@163.com.
Weiguo XuKey Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China. wgxu@ciac.ac.cn.
Jixue WangDepartment of Urology, the First Hospital of Jilin University, Changchun 130021, China. wangjx@ciac.ac.cn.
Hui GuoDepartment of Urology, the First Hospital of Jilin University, Changchun 130021, China. 18443154199@163.com.
Chunxi WangDepartment of Urology, the First Hospital of Jilin University, Changchun 130021, China. chunxi_wang@126.com.
Jianxun DingKey Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China. jxding@ciac.ac.cn.ORCID 0000-0002-5232-8863
Jilin University · CNChinese Academy of Sciences · CNShandong Tumor Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Smart polymer nanogel-assisted drug delivery systems have attracted more and more attention in cancer chemotherapy because of their well-defined morphologies and pleiotropic functions in recent years. In this work, an l-cystine-crosslinked reduction-responsive polypeptide nanogel of methoxy poly(ethylene glycol)-poly(l-phenylalanine-

Indexed as

chemotherapy">l-cystinepolypeptide nanogelprostate cancerreduction-responsivenesssmart drug delivery

Identifiers

PMID30979130
PMCPMC6432546
OpenAlexW2267485514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.