Evidence map›Paper›PMID 30979087›Full record

ArticleMolecules (Basel, Switzerland)2019

Antioxidative and Potentially Anti-inflammatory Activity of Phenolics from Lovage Leaves

Urszula Złotek, Urszula Szymanowska, Łukasz Pecio, Solomiia Kozachok, Anna Jakubczyk

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Coumarins of Lovage Roots (Metabolites · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Urszula ZłotekDepartment of Biochemistry and Food Chemistry, University of Life Sciences in Lublin, Skromna Str. 8, 20-704 Lublin, Poland. urszula.zlotek@up.lublin.pl.ORCID 0000-0001-6812-5596
Urszula SzymanowskaDepartment of Biochemistry and Food Chemistry, University of Life Sciences in Lublin, Skromna Str. 8, 20-704 Lublin, Poland. urszula.szymanowska@up.lublin.pl.
Łukasz PecioDepartment of Biochemistry and Crop Quality, Institute of Soil Science and Plant Cultivation-State Research Institute, Czartoryskich 8, 24-100 Puławy, Poland. lpecio@iung.pulawy.pl.ORCID 0000-0002-7407-6716
Solomiia KozachokDepartment of Biochemistry and Crop Quality, Institute of Soil Science and Plant Cultivation-State Research Institute, Czartoryskich 8, 24-100 Puławy, Poland. skozachok@iung.pulawy.pl.ORCID 0000-0001-8425-7652
Anna JakubczykDepartment of Biochemistry and Food Chemistry, University of Life Sciences in Lublin, Skromna Str. 8, 20-704 Lublin, Poland. anna.jakubczyk@up.lublin.pl.ORCID 0000-0002-1087-2000
University of Life Sciences in Lublin · PLInstitute of Soil Science and Plant Cultivation · PL

Funding

Narodowe Centrum Nauki SONATA 12 No 2016/23/D/NZ9/00553
6 · The paper itself

Abstract

The effect of elicitation with jasmonic acids (JA) and yeast extract (YE) on the production of phenolic compounds as well as the antioxidant and anti-inflammatory properties of phenolic extracts of lovage was evaluated. The analysis of phenolic compounds carried out with the UPLC-MS technique indicated that rutin was the dominant flavonoid, while 5-caffeoylquinic acid was the main component in the phenolic acid fraction in the lovage leaves. The application of 10 µM JA increased the content of most of the identified phenolic compounds. The highest antioxidant activities estimated as free radical scavenging activity against ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) and reducing power were determined for the sample elicited with 10 µM JA, while this value determined as iron chelating ability was the highest for the 0.1% YE-elicited lovage. The 0.1% and 1% YE elicitation also caused significant elevation of the lipoxygenase (LOX) inhibition ability, while all the concentrations of the tested elicitors significantly improved the ability to inhibit cyclooxygenase 2 (COX2) (best results were detected for the 10 µM JA and 0.1% YE2 sample). Thus, 0.1% yeast extract and 10 µM jasmonic acid proved to be most effective in elevation of the biological activity of lovage.

Indexed as

Anti-Inflammatory AgentsAntioxidantsBenzothiazolesChromatography, High Pressure LiquidCyclopentanesFree Radical ScavengersHumansLevisticumLipoxygenase InhibitorsOxylipinsPhenolsPlant ExtractsPlant LeavesRutinSulfonic AcidsTandem Mass Spectrometry2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acidAnti-Inflammatory AgentsAntioxidantsBenzothiazolesCyclopentanesFree Radical Scavengersjasmonic acidLipoxygenase InhibitorsOxylipinsPhenolsPlant ExtractsRutinSulfonic Acidsanti-inflammatory propertiesantioxidant activitieselicitationlovagephenolic compounds

Identifiers

PMID30979087
PMCPMC6480578
OpenAlexW2939511068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.