Evidence map›Paper›PMID 30979038›Full record

Trial reportNutrients2019

Effects of

Yen-Wenn Liu, Min Tze Liong, Yu-Chu Ella Chung, Hui-Yi Huang, Wu-Shun Peng, Yun-Fang Cheng, Yu-Siou Lin, Yu-Yu Wu, Ying-Chieh Tsai

2 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 136 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
136citing papers in PubMed, 16 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05194033 nacompletednot on this mapstarted 2022, after this paper: background citation

Efficacy and Safety of Oral Lactobacillus Plantarum GUANKE (CGMCC NO.21720) in Enhancement of Antibody Level After SARS-CoV-2 Vaccination: A Prospective, Randomized, Double-blind, Placebo-Controlled Trial (Trial 1)

TypeinterventionalSponsorPeking UniversityRan2022 to 2022Enrolled31ConditionsSARS-CoV-2ArmsProbiotics daily, Placebo daily
NCT05195047 nacompletednot on this mapstarted 2022, after this paper: background citation

Efficacy and Safety of Oral Lactobacillus Plantarum GUANKE (CGMCC NO.21720) in Enhancement of Antibody Level After SARS-CoV-2 Vaccination: A Prospective, Randomized, Double-blind, Placebo-Controlled Trial (Trial 2)

TypeinterventionalSponsorPeking UniversityRan2022 to 2022Enrolled44ConditionsSARS-CoV-2Arms1 week placebo(Week 1), 1 week of probiotics(Week 1), 1 week placebo(Week 2), 1 week of probiotics(Week 2), 1 week placebo(Week 3)
3 · Its place in the literature

Who cites it

136 citing papers in PubMed, 16 syntheses or guidelines pooled it.

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  4. Complementary and Alternative Medicine for Autism - A Systematic Review.Journal of autism and developmental disorders · 2025
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  10. Nutraceuticals in Psychiatric Disorders: A Systematic Review.International journal of molecular sciences · 2024
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76 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yen-Wenn LiuInstitute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei 11221, Taiwan. skywenn@gmail.com.
Min Tze LiongSchool of Industrial Technology, Universiti Sains Malaysia, Penang 11800, Malaysia. mintze.liong@usm.my.
Yu-Chu Ella ChungInstitute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei 10050, Taiwan. eesabella1126@gmail.com.
Hui-Yi HuangDepartment of Psychology, National Taiwan University, Taipei 10090, Taiwan. huanghuyiii@gmail.com.
Wu-Shun PengInstitute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei 11221, Taiwan. catpet1022@hotmail.com.
Yun-Fang ChengInstitute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei 11221, Taiwan. hiyunfang@gmail.com.
Yu-Siou LinDepartment of Psychology, National Chengchi University, Taipei 11605, Taiwan. linyusiou@gmail.com.
Yu-Yu WuYuNing Clinic, Taipei 10664, Taiwan. ruthyuyuwu@gmail.com.
Ying-Chieh TsaiInstitute of Biochemistry and Molecular Biology, National Yang-Ming University, Taipei 11221, Taiwan. tsaiyc@ym.edu.tw.

Funding

Bened Biomedical Co., Ltd. Bened Biomedical Co., Ltd. financially supports this study.
6 · The paper itself

Abstract

This four-week, randomized, double-blind, placebo-controlled study investigated the effects of

Indexed as

Lactiplantibacillus plantarumAdolescentAge FactorsAutism Spectrum DisorderChildChild BehaviorDouble-Blind MethodHumansMalePlacebosProbioticsSocial BehaviorSurveys and QuestionnairesTaiwanPlacebosanxietyautism spectrum disorder (ASD)hyperactivityLactobacillus plantarum PS128psychobiotic

Identifiers

PMID30979038
PMCPMC6521002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.