Evidence map›Paper›PMID 30979011›Full record

ArticleCancers2019

Identification of Cancer Stem Cell Molecular Markers and Effects of hsa-miR-21-3p on Stemness in Esophageal Squamous Cell Carcinoma.

Zhikui Gao, Hui Liu, Yajuan Shi, Lihong Yin, Yong Zhu, Ran Liu

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Zhikui GaoKey Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210000, China. gaozhikuijy@163.com.ORCID 0000-0003-1650-6180
Hui LiuChengdu Center for Disease Control and Prevention, Chengdu 610000, China. lh_kitty@163.com.
Yajuan ShiKey Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210000, China. syj799@163.com.
Lihong YinKey Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210000, China. lhyin@seu.edu.cn.
Yong ZhuDepartment of Environmental Health Sciences, Yale School of Public Health, New Haven, CT 06510, USA. yong.zhu@yale.edu.
Ran LiuKey Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210000, China. ranliu@seu.edu.cn.
Southeast University · CNChengdu Center for Disease Control and Prevention · CNYale University · US

Funding

National Natural Science Foundation of China 30800891National Natural Science Foundation of China 81172747National Natural Science Foundation of China 81573108National Natural Science Foundation of China 81872579New Century Excellent Talents in University from Ministry of Education NCET-13-0124Postgraduate Research & Practice Innovation Program of Jiangsu Province KYCX17_0188
6 · The paper itself

Abstract

Cancer stem cells (CSCs) are closely related to tumor resistance and tumor recurrence in esophageal squamous cell carcinoma (ESCC). The lack of specific biomarkers to identify and isolate CSCs has led to the slow progression of research on CSCs in ESCC. Here, we established a method to identify and isolate CSCs in ESCC using fluorescence-activated cell sorting with combined surface biomarkers including CD71, CD271, and CD338. CD71

Indexed as

cancer stem cellesophageal squamous cell carcinomaHsa-miR-21-3pTRAF4

Identifiers

PMID30979011
PMCPMC6521292
OpenAlexW2940344580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.