Evidence map›Paper›PMID 30979007›Full record

ArticleMolecules (Basel, Switzerland)2019

Modulation of Endocannabinoid-Binding Receptors in Human Neuroblastoma Cells by Tunicamycin.

Cinzia Rapino, Annalisa Castellucci, Anna Rita Lizzi, Annalaura Sabatucci, Clotilde B Angelucci, Daniel Tortolani, Gianna Rossi, Gabriele D'Andrea, Mauro Maccarrone

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Endocannabinoid signaling pathways: beyond CB1R and CB2R.Journal of cell communication and signaling · 2021
    Review
  5. Neurobiology of cannabinoid receptor signaling
.Dialogues in clinical neuroscience · 2020
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Cinzia RapinoFaculty of Veterinary Medicine, Agriculture and Environment, University of Teramo, 64100 Teramo, Italy. crapino@unite.it.
Annalisa CastellucciDepartment of Biotechnology and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy. annacastel@libero.it.
Anna Rita LizziDepartment of Biotechnology and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy. annarita.lizzi@cc.univaq.it.
Annalaura SabatucciFaculty of Biosciences and Technology for Food, Agriculture and Environment, University of Teramo, 64100 Teramo, Italy. alsabatucci@unite.it.ORCID 0000-0002-8004-2547
Clotilde B AngelucciFaculty of Veterinary Medicine, Agriculture and Environment, University of Teramo, 64100 Teramo, Italy. bcangelucci@unite.it.ORCID 0000-0003-4419-3070
Daniel TortolaniFaculty of Veterinary Medicine, Agriculture and Environment, University of Teramo, 64100 Teramo, Italy. dtortolani@unite.it.ORCID 0000-0002-6704-9023
Gianna RossiDepartment of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy. gianna.rossi@cc.univaq.it.
Gabriele D'AndreaDepartment of Biotechnology and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy. gabriele.dandrea@cc.univaq.it.
Mauro MaccarroneDepartment of Medicine, Campus Bio-Medico University of Rome, 00128 Rome, Italy. m.maccarrone@unicampus.it.ORCID 0000-0002-3990-2963
University of L'Aquila · ITUniversity of Teramo · ITUniversità Campus Bio-Medico · IT

Funding

Italian Ministry of Education, University and Research (MIUR) PRIN 2015 to M.M.
6 · The paper itself

Abstract

Endocannabinoid (eCB)-binding receptors can be modulated by several ligands and membrane environment, yet the effect of glycosylation remains to be assessed. In this study, we used human neuroblastoma SH-SY5Y cells to interrogate whether expression, cellular localization, and activity of eCB-binding receptors may depend on

Indexed as

Cell Line, TumorCell MembraneEndocannabinoidsFlow CytometryGlycosylationHumansLigandsMicroscopy, ConfocalNeuroblastomaPeptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine AmidaseReceptors, CannabinoidTRPV Cation ChannelsTunicamycinEndocannabinoidsLigandsPeptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine AmidaseReceptors, CannabinoidTRPV1 protein, humanTRPV Cation ChannelsTunicamycinendocannabinoid-binding receptorsN-acetylglucosamineSH-SY5Y cellstunicamycin

Identifiers

PMID30979007
PMCPMC6479803
OpenAlexW2936220316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.