Evidence map›Paper›PMID 30978904›Full record

ArticleAntioxidants (Basel, Switzerland)2019

Water- and Fat-Soluble Antioxidants in Human Seminal Plasma and Serum of Fertile Males.

Giacomo Lazzarino, Ilaria Listorti, Gabriele Bilotta, Talia Capozzolo, Angela Maria Amorini, Salvatore Longo, Giuseppe Caruso, Giuseppe Lazzarino, Barbara Tavazzi, Pasquale Bilotta

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Pooled it
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  16. The therapeutic potential of carnosine: Focus on cellular and molecular mechanisms.Current research in pharmacology and drug discovery · 2023
    Review
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  18. Effects of carnosine on the embryonic development and TiOFrontiers in veterinary science · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Giacomo LazzarinoInstitute of Biochemistry and Clinical Biochemistry, Catholic University of Rome, Largo F. Vito 1, 00168 Rome, Italy. giacomo.lazzarino@unicatt.it.
Ilaria ListortiAlma Res Fertility Center, Centro di Fecondazione Assistita Alma Res, Via Parenzo 12, 00199 Rome, Italy. laboratorio@almares.it.
Gabriele BilottaAlma Res Fertility Center, Centro di Fecondazione Assistita Alma Res, Via Parenzo 12, 00199 Rome, Italy. bilotta.oblomov@gmail.com.
Talia CapozzoloAlma Res Fertility Center, Centro di Fecondazione Assistita Alma Res, Via Parenzo 12, 00199 Rome, Italy. taliacapozzolo@almares.it.
Angela Maria AmoriniDepartment of Biomedical and Biotechnological Sciences, Division of Medical Biochemistry, University of Catania, Viale A. Doria 6, 95125 Catania, Italy. amorini@unict.it.ORCID 0000-0003-3525-9955
Salvatore LongoLTA-Biotech srl, Viale Don Orione, 3D, 95047 Paternò (CT), Italy. salvo.longo@hotmail.it.
Giuseppe CarusoOasi Research Institute-IRCCS, Via Conte Ruggero, 73, 94018 Troina (EN), Italy. forgiuseppecaruso@gmail.com.ORCID 0000-0003-1571-5327
Giuseppe LazzarinoDepartment of Biomedical and Biotechnological Sciences, Division of Medical Biochemistry, University of Catania, Viale A. Doria 6, 95125 Catania, Italy. lazzarig@unict.it.ORCID 0000-0002-5917-7279
Barbara TavazziInstitute of Biochemistry and Clinical Biochemistry, Catholic University of Rome, Largo F. Vito 1, 00168 Rome, Italy. barbara.tavazzi@unicatt.it.ORCID 0000-0001-8743-0895
Pasquale BilottaAlma Res Fertility Center, Centro di Fecondazione Assistita Alma Res, Via Parenzo 12, 00199 Rome, Italy. pasquale.bilotta@almares.it.
Università Cattolica del Sacro Cuore · ITUniversity of Catania · ITOasi Maria SS · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactive oxygen species (ROS) are physiologically involved in functions like sperm maturation, capacitation and acrosome reaction, but their excess is involved in male infertility. Antioxidants in seminal plasma (SP) are an important factor balancing physiologic and harmful ROS activities. In this study, we determined and compared the full profiles of the water- and fat-soluble antioxidants in SP and serum of 15 healthy fertile subjects (ranging between the ages of 35 and 42 years). Ejaculates were obtained after 2⁻5 days of sexual abstinence. After liquefaction and withdrawal of an aliquot for the sperm count, samples were centrifuged to obtain SP. Thirty min after semen donation, a venous blood sample was collected from each subject. Donors with lower SP concentrations of ascorbic acid (

Indexed as

fat-soluble antioxidantshuman seminal plasmahuman serummale infertilityoxidative/nitrosative stressreactive oxygen specieswater-soluble antioxidants

Identifiers

PMID30978904
PMCPMC6523754
OpenAlexW2937945397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.