ReviewFungal genetics and biology : FG & B2019
The role of fungi in C. difficile infection: An underappreciated transkingdom interaction.
Review in Fungal genetics and biology : FG & B, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Repurposing azole antifungals as rapid bactericidal, membrane-disruptive therapeutics againstMicrobiology spectrum · 2026Article
- Effect of calf separation on gut microbiome and fecal metabolome of mother in the captive Yangtze finless porpoise (Neophocaena asiaeorientalis asiaeorientalis).International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Effects of forages on the microbiota of crossed sheep on cold Plateau.Animal biotechnology · 2024Article
- The role of gut fungi in Clostridioides difficile infection.Biomedical journal · 2024Review
- Pre-colonization with the fungusmSphere · 2023Article
- Identification of intestinal and fecal microbial biomarkers using a porcine social stress model.Frontiers in microbiology · 2023Article
- Gut microbiota profiles in diarrheic patients with co-occurrence of Clostridioides difficile and Blastocystis.PloS one · 2021Article
- Let's Get Physical: Bacterial-Fungal Interactions and Their Consequences in Agriculture and Health.Journal of fungi (Basel, Switzerland) · 2020Review
- The gut, the bad and the harmless: Candida albicans as a commensal and opportunistic pathogen in the intestine.Current opinion in microbiology · 2020Review
- Lipid Species in the GI Tract are Increased by the Commensal FungusJournal of fungi (Basel, Switzerland) · 2020Article
- The gut mycobiome: The overlooked constituent of clinical outcomes and treatment complications in patients with cancer and other immunosuppressive conditions.PLoS pathogens · 2020Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Novel culture independent technologies have further elucidated the composition of the human mycobiome, though the role of fungi in human health and disease remains largely unknown. Recent studies have suggested conflicting roles for fungi in the gastrointestinal tract, underscoring the complexity of the interactions between the mycobiome, its bacterial counterpart, and the host. One key example is the observation that fungal taxa are overrepresented in patients with Clostridioides difficile infection (CDI), suggesting a role for fungi in this disease. Recent studies in murine models have demonstrated the ability of the commensal fungus Candida albicans to alter the course of CDI, supporting the notion that fungi play a role in this infection. This review summarizes current data on fungi and CDI, and shows that views of the dysbiotic state that is central to the pathogenesis of CDI are incomplete without consideration of the mycobiome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.