ArticleAmerican journal of respiratory cell and molecular biology2019
Organophosphorus Pesticides Induce Cytokine Release from Differentiated Human THP1 Cells.
Article in American journal of respiratory cell and molecular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 37 citations in OpenAlex.
- Associations Between Urinary Pesticide Metabolites and Serum Inflammatory Biomarkers in Adolescents Living in an Agricultural Region.Exposure and health · 2025Article
- Biomarkers of Pesticide Exposure in a Traditional Brazilian Amazon Community.International journal of environmental research and public health · 2024Article
- Protective effect ofToxicology reports · 2024Article
- Article
- Article
- Cnr1Chemico-biological interactions · 2023Article
- Molecular Mechanisms of Acute Organophosphate Nephrotoxicity.International journal of molecular sciences · 2022Review
- Article
- Organophosphorus Pesticides as Modulating Substances of Inflammation through the Cholinergic Pathway.International journal of molecular sciences · 2022Review
- Occupational causes of chronic obstructive pulmonary disease: an update.Current opinion in allergy and clinical immunology · 2022Review
- Luteolin activates M2 macrophages and suppresses M1 macrophages by upregulation of hsa_circ_0001326 in THP-1 derived macrophages.Bioengineered · 2022Article
- Organophosphorus pesticides exhibit compound specific effects in rat precision-cut lung slices (PCLS): mechanisms involved in airway response, cytotoxicity, inflammatory activation and antioxidative defense.Archives of toxicology · 2022Article
- Effects of Chlorpyrifos on Serine Hydrolase Activities, Lipid Mediators, and Immune Responses in Lungs of Neonatal and Adult Mice.Chemical research in toxicology · 2021Article
- Direct C-H photoarylation of diazines using aryldiazonium salts and visible-light.RSC advances · 2020Article
- Fucoidan protects against subacute diazinon-induced oxidative damage in cardiac, hepatic, and renal tissues.Environmental science and pollution research international · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Epidemiologic studies link organophosphorus pesticides (OPs) to increased incidence of asthma. In guinea pigs, OP-induced airway hyperreactivity requires macrophages and TNF-α. Here, we determined whether OPs interact directly with macrophages to alter cytokine expression or release. Human THP1 cells were differentiated into macrophages and then exposed to parathion, chlorpyrifos, or diazinon, or their oxon, phosphate, or phosphorothioate metabolites for 24 hours in the absence or presence of reagents that block cholinergic receptors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.