Trial reportPloS one2019
Calculated arterial blood gas values from a venous sample and pulse oximetry: Clinical validation.
Trial report in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 24 citations in OpenAlex.
- Transforming the Venous Blood Gas to the Arterial Blood Gas from Concurrent Measurements.Kidney360 · 2026Article
- Human neutrophil lipocalin, procalcitonin, c-reactive protein, and leucocyte count for prediction of bacterial sepsis in emergency department patients.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025Article
- Relationship Between Phenotypical and Echocardiographic Findings With Pulmonary Hypertension in COPD Patients.Pulmonary circulation · 2025Article
- Comparison of venous and calculated blood gas values to arterial values in critically ill patients.Acta anaesthesiologica Scandinavica · 2025Article
- Motion resistance in peripheral oxygen saturation monitoring using Biolight Analog SpOBMC anesthesiology · 2024Article
- Comparison of mathematically arterialised venous blood gas sampling with arterial, capillary, and venous sampling in adult patients with hypercapnic respiratory failure: a single-centre longitudinal cohort study.BMJ open respiratory research · 2023Article
- Pulse oximetry for the diagnosis and management of acute respiratory distress syndrome.The Lancet. Respiratory medicine · 2022Review
- Mathematically arterialised venous blood is a stable representation of patient acid-base status at steady state following acute transient changes in ventilation.Journal of clinical monitoring and computing · 2022Article
- Oximetry neither to prescribe long-term oxygen therapy nor to screen for severe hypoxaemia.ERJ open research · 2021Article
- Trending peripheral venous PCOBMJ open respiratory research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundArterial blood gases (ABG) are essential for assessment of patients with severe illness, but sampling is difficult in some settings and more painful than for peripheral venous blood gas (VBG). Venous to Arterial Conversion (v-TAC; OBIMedical ApS, Denmark) is a method to calculate ABG values from a VBG and pulse oximetry (SpO2). The aim was to validate v-TAC against ABG for measuring pH, carbon dioxide (pCO2) and oxygenation (pO2).
methodsOf 103 sample sets, 87 paired ABGs and VBGs with SpO2 from 46 inpatients eligible for ABG met strict sampling criteria. Agreement was evaluated using mean difference with 95% limits of agreement (LoA) and Bland-Altman plots.
resultsv-TAC had very high agreement with ABG for pH (mean diff(ABG-v-TAC) -0.001; 95% LoA -0.017 to 0.016), pCO2 (-0.14 kPa; 95% LoA -0.46 to 0.19) and moderate to high for pO2 (-0.28 kPa; 95% LoA -1.31 to 0.76). For detecting hypercapnia (PaCO2>6.0 kPa), v-TAC had sensitivity 100%, specificity 93.8% and accuracy 97%. The accuracy of v-TAC for detecting hypoxemia (PaO2<8.0 kPa) was comparable to that of pulse oximetry. Agreement with ABG was higher for v-TAC than for VBG for all analyses.
conclusionCalculated arterial blood gases (v-TAC) from a venous sample and pulse oximetry were comparable to ABG values and may be useful for evaluation of blood gases in clinical settings. This could reduce the logistic burden of arterial sampling, facilitate improved screening and follow-up and reduce patient pain.
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