ArticleJournal of the American Geriatrics Society2019
Cumulative Prognostic Score Predicting Mortality in Patients Older Than 80 Years Admitted to the ICU.
Article in Journal of the American Geriatrics Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Methods of Assessing Frailty in the Critically Ill: A Systematic Review of the Current Literature.Gerontology · 2022Pooled it
- Sublingual microcirculatory assessment on admission independently predicts the outcome of old intensive care patients suffering from shock.Scientific reports · 2024Trial
- Early prognostication of septic shock in Korean adults aged 80 years and over: serum albumin combined with Sequential Organ Failure Assessment Score.Acute and critical care · 2026Article
- Characteristics, Outcomes and Recovery of Patients 65 Years or Older Admitted to Swedish Intensive Care Units: A Protocol for a Longitudinal Observational Multicentre Study.Nursing in critical care · 2025Article
- Hospitalization of very old critically ill patients in medical intermediate care units in France: a nationwide population-based study.Annals of intensive care · 2025Article
- Prognosticating the outcome of intensive care in older patients-a narrative review.Annals of intensive care · 2024Review
- Frailty assessment in critically ill older adults: a narrative review.Annals of intensive care · 2024Review
- The association of premorbid conditions with 6-month mortality in acutely admitted ICU patients over 80 years.Annals of intensive care · 2024Article
- A scoping review of older patients' health-related quality of life, recovery and well-being after intensive care.Nursing open · 2023Article
- Whole transcriptome analysis to explore the impaired immunological features in critically ill elderly patients with sepsis.Journal of translational medicine · 2023Article
- Impact on 6-month outcomes of hospital trajectory in critically ill older patients: analysis of the ICE-CUB2 clinical trial.Annals of intensive care · 2022Article
- ProPACC: Protocol for a Trial of Integrated Specialty Palliative Care for Critically Ill Older Adults.Journal of pain and symptom management · 2022Article
- State of the Art of Machine Learning-Enabled Clinical Decision Support in Intensive Care Units: Literature Review.JMIR medical informatics · 2022Review
- Physicians' decreased tendency to choose palliative care for patients with advanced dementia between 1999 and 2015.BMC palliative care · 2021Article
- ICU-Mortality in Old and Very Old Patients Suffering From Sepsis and Septic Shock.Frontiers in medicine · 2021Article
- The good, the bad and the ugly: pandemic priority decisions and triage.Journal of medical ethics · 2020Article
- Frailty in Critical Care Medicine: A Review.Anesthesia and analgesia · 2020Review
- Community-acquired pneumonia in critically ill very old patients: a growing problem.European respiratory review : an official journal of the European Respiratory Society · 2020Review
Corrections and comments
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Authors and funding
26 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo develop a scoring system model that predicts mortality within 30 days of admission of patients older than 80 years admitted to intensive care units (ICUs).
designProspective cohort study.
settingA total of 306 ICUs from 24 European countries.
participantsOlder adults admitted to European ICUs (N = 3730; median age = 84 years [interquartile range = 81-87 y]; 51.8% male). MEASUREMENTS: Overall, 24 variables available during ICU admission were included as potential predictive variables. Multivariable logistic regression was used to identify independent predictors of 30-day mortality. Model sensitivity, specificity, and accuracy were evaluated with receiver operating characteristic curves.
resultsThe 30-day-mortality was 1562 (41.9%). In multivariable analysis, these variables were selected as independent predictors of mortality: age, sex, ICU admission diagnosis, Clinical Frailty Scale, Sequential Organ Failure Score, invasive mechanical ventilation, and renal replacement therapy. The discrimination, accuracy, and calibration of the model were good: the area under the curve for a score of 10 or higher was .80, and the Brier score was .18. At a cut point of 10 or higher (75% of all patients), the model predicts 30-day mortality in 91.1% of all patients who die.
conclusionA predictive model of cumulative events predicts 30-day mortality in patients older than 80 years admitted to ICUs. Future studies should include other potential predictor variables including functional status, presence of advance care plans, and assessment of each patient's decision-making capacity.
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