Evidence map›Paper›PMID 30977360›Full record

ArticleChemical research in toxicology2019

Hydroxyl Radicals in E-Cigarette Vapor and E-Vapor Oxidative Potentials under Different Vaping Patterns.

Yeongkwon Son, Vladimir Mishin, Jeffrey D Laskin, Gediminas Mainelis, Olivia A Wackowski, Cristine Delnevo, Stephan Schwander, Andrey Khlystov, Vera Samburova, Qingyu Meng

Open access · greenAbstract read
In one paragraph

Article in Chemical research in toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 4 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 4 syntheses or guidelines pooled it, 86 citations in OpenAlex.

  1. Pulmonary effects of e-liquid flavors: a systematic review.Journal of toxicology and environmental health. Part B, Critical reviews · 2022
    Pooled it
  2. Lung Damage Caused by Heated Tobacco Products and Electronic Nicotine Delivery Systems: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  3. Pooled it
  4. Pooled it
  5. E‑Cigarettes Generate Gas Phase Ions.Environment & health (Washington, D.C.) · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Cannabis concentrate vaping chemistry.Frontiers in toxicology · 2025
    Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Does vaping increase the likelihood of SARS-CoV-2 infection? Paradoxically yes and no.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  17. Vaping Dose, Device Type, and E-Liquid Flavor are Determinants of DNA Damage in Electronic Cigarette Users.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yeongkwon SonDepartment of Environmental and Occupational Health, School of Public Health , Rutgers University , Piscataway , New Jersey 08854 , United States.ORCID 0000-0002-4773-6838
Vladimir MishinEnvironmental and Occupational Health Sciences Institute , Rutgers University , Piscataway , New Jersey 08854 , United States.
Jeffrey D LaskinEnvironmental and Occupational Health Sciences Institute , Rutgers University , Piscataway , New Jersey 08854 , United States.
Gediminas MainelisDepartment of Environmental Sciences , Rutgers University , New Brunswick , New Jersey 08901 , United States.ORCID 0000-0002-5837-0413
Olivia A WackowskiCenter for Tobacco Studies, School of Public Health , Rutgers University , Piscataway , New Jersey , United States.
Cristine DelnevoCenter for Tobacco Studies, School of Public Health , Rutgers University , Piscataway , New Jersey , United States.
Stephan SchwanderDepartment of Environmental and Occupational Health, School of Public Health , Rutgers University , Piscataway , New Jersey 08854 , United States.
Andrey KhlystovDivision of Atmospheric Sciences , Desert Research Institute , Reno , Nevada 89512 , United States.
Vera SamburovaDivision of Atmospheric Sciences , Desert Research Institute , Reno , Nevada 89512 , United States.
Qingyu MengDepartment of Environmental and Occupational Health, School of Public Health , Rutgers University , Piscataway , New Jersey 08854 , United States.
Rutgers, The State University of New Jersey · USDesert Research Institute · US

Funding

UMDNJ/Rutgers University CounterACT Research Center of ExcellenceU54AR055073 · NIAMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI SINKO, PATRICK J. · 2006 to 2024
$71.4M
Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI BRIAN T BUCKLEY · 1988 to 2026
$47.4M
Developing Drugs to Mitigate Parathion IntoxicationU01NS079249 · NINDS · RBHS-SCHOOL OF PUBLIC HEALTH · PI LASKIN, JEFFREY D, RICHARDSON, JASON R · 2013 to 2017
$4.0M
Advanced Development of Drugs to Mitigate Parathion IntoxicationU01NS108956 · NINDS · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI LASKIN, JEFFREY D, RICHARDSON, JASON R · 2018 to 2022
$3.9M
Developing and testing warning statements about e-cigarettesK01CA189301 · NCI · RBHS-SCHOOL OF PUBLIC HEALTH · PI WACKOWSKI, OLIVIA · 2014 to 2016
$478k
NCI NIH HHS K01 CA189301NIAMS NIH HHS U54 AR055073NIEHS NIH HHS P30 ES005022NINDS NIH HHS U01 NS079249NINDS NIH HHS U01 NS108956
6 · The paper itself

Abstract

Available studies, while limited in number, suggest that e-cigarette vaping induces oxidative stress, with one potential mechanism being the direct formation of reactive oxygen species (ROS) in e-vapor. In the present studies, we measured the formation of hydroxyl radical (

Indexed as

Electronic Nicotine Delivery SystemsVapingE-Cigarette VaporFlavoring AgentsHumansHydroxyl RadicalLigandsOxidation-ReductionE-Cigarette VaporFlavoring AgentsHydroxyl RadicalLigands

Identifiers

PMID30977360
PMCPMC6579624
OpenAlexW2936266369

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.