Evidence map›Paper›PMID 30977084›Full record

ArticleMolecular biology reports2019

Blood pressure lowering effect of Ficus deltoidea var kunstleri in spontaneously hypertensive rats: possible involvement of renin-angiotensin-aldosterone system, endothelial function and anti-oxidant system.

Norasikin Ab Azis, Renu Agarwal, Nafeeza Mohd Ismail, Nor Hadiani Ismail, Mohd Saleh Ahmad Kamal, Zurain Radjeni, Harbindar Jeet Singh

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Crude extract ofExploration of targeted anti-tumor therapy · 2023
    Article
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Norasikin Ab AzisFaculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Sungai Buloh, Selangor, Malaysia.
Renu AgarwalFaculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Sungai Buloh, Selangor, Malaysia.
Nafeeza Mohd IsmailFaculty of Medicine, International Medical University, Bukit Jalil, Kuala Lumpur, Malaysia.
Nor Hadiani IsmailAtta-ur-Rahman Institute of Natural Product Discovery (AuRIns), Faculty of Pharmacy, Universiti Teknologi MARA, Cawangan Selangor, Puncak Alam Campus, Kuala Seangor, Selangor, Malaysia.
Mohd Saleh Ahmad KamalFaculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Sungai Buloh, Selangor, Malaysia.
Zurain RadjeniFaculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Sungai Buloh, Selangor, Malaysia.
Harbindar Jeet SinghFaculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Sungai Buloh, Selangor, Malaysia. hjsingh@salam.uitm.edu.my.ORCID http://orcid.org/0000-0002-0805-0614
Hospital Sungai Buloh · MYIMU University · MY

Funding

Ministry of Agriculture, Malaysia (MOA) (100-RMI/MOA/ 16/62).
6 · The paper itself

Abstract

This study investigated the effects of a standardised ethanol and water extract of Ficus deltoidea var. Kunstleri (FDK) on blood pressure, renin-angiotensin-aldosterone system (RAAS), endothelial function and antioxidant system in spontaneously hypertensive rats (SHR). Seven groups of male SHR were administered orally in volumes of 0.5 mL of either FDK at doses of 500, 800, 1000 and 1300 mg kg

Indexed as

Angiotensin IIAnimalsAntioxidantsBlood PressureCaptoprilDisease Models, AnimalDrugs, Chinese HerbalFicusHypertensionLosartanMaleNitric Oxide Synthase Type IIIPeptidyl-Dipeptidase APlant ExtractsRatsRats, Inbred SHRAngiotensin IIAntioxidantsCaptoprilDrugs, Chinese HerbalLosartanNitric Oxide Synthase Type IIINos3 protein, ratPeptidyl-Dipeptidase APlant ExtractsACEACE2Ficus deltoideaHypertensionRAASSHR

Identifiers

PMID30977084
OpenAlexW2938243492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.