ArticleJournal of neuro-oncology2019
Evaluation of pediatric glioma outcomes using intraoperative MRI: a multicenter cohort study.
Article in Journal of neuro-oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Intraoperative MRI versus intraoperative ultrasound in pediatric brain tumor surgery: is expensive better than cheap? A review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Pooled it
- IgG4-Related Disease of the Skull and Skull Base-A Systematic Review and Report of Two Cases.World neurosurgery · 2021Pooled it
- Intraoperative MRI in pediatric brain tumor surgery: Optimizing surgical decision-making and extent of resection.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Observational
- Intraoperative rapid molecular diagnosis aids glioma subtyping and guides precise surgical resection.Annals of clinical and translational neurology · 2024Article
- The RAPID Consortium: A Platform for Clinical and Translational Pituitary Tumor Research.Journal of neurological surgery. Part B, Skull base · 2024Article
- Evaluating the use of intraoperative magnetic resonance imaging in paediatric brain tumour resection surgeries: a literature review.Journal of medical radiation sciences · 2023Review
- A Low Subfrontal Dural Opening for Operative Management of Anterior Skull Base Lesions.Journal of neurological surgery. Part B, Skull base · 2023Article
- Advanced intraoperative MRI in pediatric brain tumor surgery.Frontiers in physiology · 2023Review
- Survival After Resection of Newly-Diagnosed Intracranial Grade II Ependymomas: An Initial Multicenter Analysis and the Logistics of Intraoperative Magnetic Resonance Imaging.World neurosurgery · 2022Article
- Neoadjuvant stereotactic radiosurgery for brain metastases: a new paradigm.Neurosurgical focus · 2022Article
- Intraoperative MRI for Brain Tumors.Journal of neuro-oncology · 2021Review
- Combining Pre-operative Diffusion Tensor Images and Intraoperative Magnetic Resonance Images in the Navigation Is Useful for Detecting White Matter Tracts During Glioma Surgery.Frontiers in neurology · 2021Article
- Immune Checkpoint-Associated Locations of Diffuse Gliomas Comparing Pediatric With Adult Patients Based on Voxel-Wise Analysis.Frontiers in immunology · 2021Article
- Using Histopathology to Assess the Reliability of Intraoperative Magnetic Resonance Imaging in Guiding Additional Brain Tumor Resection: A Multicenter Study.Neurosurgery · 2020Article
- Image Guidance in Cranial Neurosurgery: How a Six-Ton Magnet and Fluorescent Colors Make Brain Tumor Surgery Better.Missouri medicineReview
- Rapid intraoperative diagnosis of pediatric brain tumors using Raman spectroscopy: A machine learning approach.Neuro-oncology advancesArticle
Corrections and comments
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Authors and funding
25 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe use of intraoperative MRI (iMRI) during treatment of gliomas may increase extent of resection (EOR), decrease need for early reoperation, and increase progression-free and overall survival, but has not been fully validated, particularly in the pediatric population.
objectiveTo assess the accuracy of iMRI to identify residual tumor in pediatric patients with glioma and determine the effect of iMRI on decisions for resection, complication rates, and other outcomes.
methodsWe retrospectively analyzed a multicenter database of pediatric patients (age ≤ 18 years) who underwent resection of pathologically confirmed gliomas.
resultsWe identified 314 patients (mean age 9.7 ± 4.6 years) with mean follow-up of 48.3 ± 33.6 months (range 0.03-182.07 months) who underwent surgery with iMRI. There were 201 (64.0%) WHO grade I tumors, 57 (18.2%) grade II, 24 (7.6%) grade III, 9 (2.9%) grade IV, and 23 (7.3%) not classified. Among 280 patients who underwent resection using iMRI, 131 (46.8%) had some residual tumor and underwent additional resection after the first iMRI. Of the 33 tissue specimens sent for pathological analysis after iMRI, 29 (87.9%) showed positive tumor pathology. Gross total resection was identified in 156 patients (55.7%), but this was limited by 69 (24.6%) patients with unknown EOR.
conclusionsAnalysis of the largest multicenter database of pediatric gliomas resected using iMRI demonstrated additional tumor resection in a substantial portion of cases. However, determining the impact of iMRI on EOR and outcomes remains challenging because iMRI use varies among providers nationally. Continued refinement of iMRI techniques for use in pediatric patients with glioma may improve outcomes.
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