Evidence map›Paper›PMID 30977041›Full record

ArticleNeuroscience bulletin2019

Enhancement of Aggression Induced by Isolation Rearing is Associated with a Lack of Central Serotonin.

Yiqiong Liu, Yunong Sun, Xiaoyan Zhao, Ji-Young Kim, Lu Luo, Qian Wang, Xiaolu Meng, Yonghui Li, Nan Sui, Zhou-Feng Chen and 3 more

Open access · greenAbstract read
In one paragraph

Article in Neuroscience bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Yiqiong LiuState Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing, 100871, China.
Yunong SunHendrix College, Conway, AR, 72032, USA.
Xiaoyan ZhaoDepartment of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100005, China.
Ji-Young KimDepartment of Anesthesiology, Department of Psychiatry, Department of Developmental Biology, Center for the Study of Itch, Washington University School of Medicine, Saint Louis, MO, 63110, USA.
Lu LuoSchool of Psychological and Cognitive Sciences, Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, 100871, China.
Qian WangSchool of Psychological and Cognitive Sciences, Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, 100871, China.
Xiaolu MengKey Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, 100101, China.
Yonghui LiKey Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, 100101, China.
Nan SuiKey Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, 100101, China.
Zhou-Feng ChenDepartment of Anesthesiology, Department of Psychiatry, Department of Developmental Biology, Center for the Study of Itch, Washington University School of Medicine, Saint Louis, MO, 63110, USA.
Chuxiong PanDepartment of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100005, China.
Liang LiSchool of Psychological and Cognitive Sciences, Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, 100871, China. liangli@pku.edu.cn.
Yan ZhangState Key Laboratory of Membrane Biology, College of Life Sciences, Peking University, Beijing, 100871, China. yanzhang@pku.edu.cn.
Chinese Institute for Brain Research · CNInstitute of Psychology, Chinese Academy of Sciences · CNPeking University · CNWashington University in St. Louis · USBeijing Tongren Hospital · CNCapital Medical University · CNHendrix College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isolation rearing (IR) enhances aggressive behavior, and the central serotonin (5-hydroxytryptamine, 5-HT) system has been linked to IR-induced aggression. However, whether the alteration of central serotonin is the cause or consequence of enhanced aggression is still unknown. In the present study, using mice deficient in central serotonin Tph2

Indexed as

AggressionAnimalsFemaleMaleMaze LearningMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicReflex, StartleSerotoninSocial IsolationSerotonin5-HTAggressionDopamineLmx1bSocial isolation

Identifiers

PMID30977041
PMCPMC6754493
OpenAlexW2939566475

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.