Evidence map›Paper›PMID 30977024›Full record

ArticleInternational ophthalmology2019

Multimodal imaging including optical coherence tomography angiography in patients with type B Niemann-Pick disease.

Selim Bolukbasi, Cezmi Dogan, Ertugrul Kiykim, Akin Cakir, Burak Erden, Alper Halil Bayat, Mustafa Nuri Elcioglu, Ayse Cigdem Aktuglu Zeybek

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Article in International ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Selim BolukbasiDepartment of Ophthalmology, Okmeydani Training and Research Hospital, University of Health Sciences, Istanbul, Turkey. selimbolukbasi@hotmail.com.
Cezmi DoganDepartment of Ophthalmology, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey.
Ertugrul KiykimDepartment of Pediatrics, Division of Nutrition and Metabolism, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey.
Akin CakirDepartment of Ophthalmology, Okmeydani Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Burak ErdenDepartment of Ophthalmology, Okmeydani Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Alper Halil BayatDepartment of Ophthalmology, Okmeydani Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Mustafa Nuri ElciogluDepartment of Ophthalmology, Okmeydani Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Ayse Cigdem Aktuglu ZeybekDepartment of Pediatrics, Division of Nutrition and Metabolism, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey.
Istanbul University · TROkmeydanı Eğitim ve Araştırma Hastanesi · TRSağlık Bilimleri Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate accumulation patterns of deposits in retinal layers of type B Niemann-Pick patients by multimodal imaging.

methodsSeven patients with type B Niemann-Pick disease were included in this study. All participants underwent a complete ophthalmologic evaluation, high-resolution digital colour imaging, spectral-domain optical coherence tomography, blue light fundus autofluorescence and optical coherence tomography angiography (OCTA).

resultsWe demonstrated different accumulation patterns in the retinal ganglion cell layer, the retinal nerve fibre layer and the subfoveolar region by multimodal imaging. Local retinal capillary nonflow areas in the superficial plexus, increased vascular tortuosity and deformed foveal avascular areas were shown in OCTA scans.

conclusionMultimodal imaging including OCTA is a useful technique for the identification of different types of accumulation patterns, diagnosis and follow-up of type B Niemann-Pick patients.

Indexed as

Multimodal ImagingAdolescentChildFemaleFluorescein AngiographyFollow-Up StudiesFundus OculiHumansMaleNiemann-Pick Disease, Type BRetinal DiseasesRetinal Ganglion CellsRetinal VesselsRetrospective StudiesTomography, Optical CoherenceVisual AcuityMultimodal imagingNiemann–PickOptical coherence tomographyOptical coherence tomography angiography

Identifiers

PMID30977024
OpenAlexW2935972002

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.