Evidence map›Paper›PMID 30976968›Full record

ArticleParasitology research2019

Massive Cryptosporidium infections and chronic diarrhea in HIV-negative patients.

Łukasz Pielok, Szymon Nowak, Matylda Kłudkowska, Krystyna Frąckowiak, Łukasz Kuszel, Paweł Zmora, Jerzy Stefaniak

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Parasitology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Molecular prevalence ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021
    Article
  2. First Molecular Characterization ofPathogens (Basel, Switzerland) · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Łukasz PielokDepartment and Clinic of Tropical and Parasitic Diseases, Poznań University of Medical Sciences, Przybyszewskiego Street, 60-355, Poznań, Poland. l.augustyn@wp.pl.ORCID http://orcid.org/0000-0002-4104-0610
Szymon NowakDepartment and Clinic of Tropical and Parasitic Diseases, Poznań University of Medical Sciences, Przybyszewskiego Street, 60-355, Poznań, Poland.
Matylda KłudkowskaDepartment and Clinic of Tropical and Parasitic Diseases, Poznań University of Medical Sciences, Przybyszewskiego Street, 60-355, Poznań, Poland.
Krystyna FrąckowiakCentral Laboratory of Microbiology, H. Święcicki University Hospital, Poznań, Poland.
Łukasz KuszelDepartment of Medical Genetics, Poznań University of Medical Sciences, Poznań, Poland.
Paweł ZmoraInstitute of Bioorganic Chemistry Polish Academy of Sciences, Poznań, Poland.
Jerzy StefaniakDepartment and Clinic of Tropical and Parasitic Diseases, Poznań University of Medical Sciences, Przybyszewskiego Street, 60-355, Poznań, Poland.
Poznan University of Medical Sciences · PLHeliodor Swiecicki Clinical Hospital · PLInstitute of Bioorganic Chemistry, Polish Academy of Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protozoa of the genus Cryptosporidium are common parasites of domestic and wild animals-mammals, birds, reptiles, and fishes. The invasive forms are thick-walled oocysts, which can be present in water supplies, on fruits, vegetables, or in the soil contaminated with feces. In this work, we describe three cases of middle-aged persons with massive Cryptosporidium hominis infection and chronic diarrhea with no immunological abnormalities and no history of previous travels to tropical countries. The lesions discovered during colonoscopy within the large intestine-cryptitis and the histopathological changes were related to massive cryptosporidiosis. All these statements indicate necessity of parasitological stool examination in cases with chronic diarrhea in which no etiological agents are detected, but not only in HIV positive individuals. Parasite's eradication leads to symptom disappearance as well as improvement of histopathological mucosa alterations.

Indexed as

AnimalsCryptosporidiosisCryptosporidiumDiarrheaDNA, ProtozoanDrinking WaterFecesFemaleHIVHIV InfectionsHumansIntestine, LargeMaleMiddle AgedMolecular TypingOocystsDNA, ProtozoanDrinking WaterChronic diarrheaCryptitisCryptosporidiosisCryptosporidium spp.DiarrheaImmunocompetentNitazoxanide

Identifiers

PMID30976968
PMCPMC6520477
OpenAlexW2939244330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.