SynthesisWorld journal of urology2019
Oncologic outcomes after robot-assisted versus open radical cystectomy: a systematic review and meta-analysis.
Synthesis in World journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Robotic Versus Open Cystectomy for Bladder Cancer: Synthesizing the Data from Current Systematic Reviews and Meta-Analyses.Annals of surgical oncology · 2023Pooled it
- Robotic surgery in comparison to the open and laparoscopic approaches in the field of urology: a systematic review.Journal of robotic surgery · 2023Pooled it
- Demonstrating the non-inferiority of robotic radical cystectomy for cT3-cT4 urothelial carcinoma in the era of neoadjuvant chemotherapy: a propensity score-matched analysis.Journal of robotic surgery · 2025Article
- Perioperative complications and oncological outcomes of open versus robotic-assisted radical cystectomy: a propensity score-matched study.World journal of urology · 2024Article
- First case report of robot-assisted radical cystectomy and intracorporeal urinary diversion using the hinotori Surgical Robot System.Translational cancer research · 2024Article
- Intracorporeal versus extracorporeal urinary diversion in robot-assisted radical cystectomy: a systematic review and meta-analysis.International journal of clinical oncology · 2021Review
- Comparison of intracorporeal versus extracorporeal urinary diversion after robot-assisted radical cystectomy at a medium-sized facility.International journal of clinical oncology · 2021Article
- Intra-corporeal robot-assisted versus open radical cystectomy: a propensity score-matched analysis comparing perioperative and long-term survival outcomes and recurrence patterns.International journal of clinical oncology · 2021Article
- Contemporary Outcomes of Open Radical Cystectomy: a 5-Year Experience from a Tertiary Care Center.Indian journal of surgical oncology · 2021Article
- Current evidence for robotic surgery in radical cystectomy.Turkish journal of urology · 2021Review
- Intracorporeal versus extracorporeal urinary diversion after robot-assisted radical cystectomy: a pooled analysis.Gland surgery · 2021Article
- Survival after radical cystectomy for bladder cancer: Multicenter comparison between minimally invasive and open approaches.Asian journal of urology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe efficacy of RARC in oncologic outcomes compared ORC is controversial. We assess potential differences in oncologic outcomes between robot-assisted radical cystectomy (RARC) and open radical cystectomy (ORC).
methodsWe performed the literature search systematically according to the Preferred Reporting Items for Systematic Review and Meta-analysis statement. A pooled meta-analysis was performed to assess the difference in oncologic outcomes between RARC and ORC, separately in randomized controlled trials (RCTs) and non-randomized studies (NRCTs).
resultsFive RCTs and 28 NRCTs were included in this systematic review and meta-analysis. There was no difference in the rate of overall positive surgical margin (PSM) in RCTs, while NRCTs showed a lower rate for RARC. There was no difference in the soft tissue PSM rate between RARC and ORC in both RCTs and NRCTs. There was no difference in the lymph node yield by standard and extended lymph node dissection between RARC and ORC in both RCTs and NRCTs. There was no significant difference in survival outcomes between RARC and ORC in both RCTs and NRCTs.
conclusionsBased on the current evidence, there is no difference in the rate of PSMs, lymph node yield, recurrence rate and location as well as short-term survival outcomes between RARC and ORC in RCTs. In NRCTs, only PSM rates were better for RARC compared to ORC, but this was likely due to selection and reporting bias which are inherent to retrospective study designs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.